USE OF ZONA-FREE ANIMAL OVA AS A TEST-SYSTEM FOR ASSESSMENT OF FERTILIZING-CAPACITY OF HUMAN SPERMATOZOA
USE OF ZONA-FREE ANIMAL OVA AS A TEST-SYSTEM FOR ASSESSMENT OF FERTILIZING-CAPACITY OF HUMAN SPERMATOZOA
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DOI：
10.1095/biolreprod15.4.471
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发表时间：
1976-01-01
影响因子：
3.6
通讯作者：
ROGERS, BJ
中科院分区：
文献类型：
--
作者：
YANAGIMACHI, R;YANAGIMACHI, H;ROGERS, BJ
人类精子最初不能穿透无透明带的动物（仓鼠）卵子，但在体外培养几个小时后就有了这种能力。这种能力可能与精子获能的完成和顶体反应有关。当人类卵子不容易获得时，在初步评估人类精子的受精能力时，可以用无带动物卵子代替人类卵子。
Human spermatozoa are initially incapable of penetrating zona pellucida-free animal (hamster) ova but gain the ability to do so when incubated several hours in vitro. This ability may be associated with the completion of sperm capacitation and the acrosome reaction. Zona-free animal ova may be substituted for human ova in the preliminary assessment of the fertilizing capacity of human spermatozoa when human ova are not readily available.