Metal release from various grades of stainless steel exposed to synthetic body fluids
Metal release from various grades of stainless steel exposed to synthetic body fluids
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DOI：
10.1016/j.corsci.2006.05.008
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发表时间：
2007-01-01
影响因子：
8.3
通讯作者：
Leygraf, C.
中科院分区：
文献类型：
--
作者：
Herting, G.;Wallinder, I. Odnevall;Leygraf, C.
通过暴露于两种合成体液的七种等级不锈钢测定了单个合金成分的释放速率，用作肺中不同潜在暴露区域的替代物：“甘布尔溶液”（pH 7.4），代表肺深部的间质液，以及人工溶酶体液（ALF），其代表颗粒被巨噬细胞吞噬后的更酸性（pH 4.5-5）环境。所研究的所有等级不锈钢的总金属释放速率都很低（< 5 μ g cm（-2）周（-1））。与Gamble溶液（< 0.1 μ g cm（-2）week（-1））相比，ALF的更酸性环境导致显著更高的总金属释放速率（0.3-4.6 μ g cm（-2）week（-1））。(c)2006爱思唯尔有限公司保留所有权利。
Release rates of individual alloy constituents have been determined from seven grades of stainless steels exposed to two synthetic body fluids, used as surrogates for different areas of potential exposure in the lung: "Gamble's solution", (pH 7.4) that represents the interstitial fluid of the deep lung, and artificial lysosomal fluid (ALF) that represents the more acidic (pH 4.5-5) milieu of particles following their phagocytosis by macrophages. Total metal release rates from all grades of stainless steel investigated were low (< 5 mu g cm(-2) week(-1)). The more acidic environment of ALF resulted in significantly higher total metal release rates (0.3-4.6 mu g cm(-2) week(-1)) compared to Gamble's solution (< 0.1 mu g cm(-2) week(-1)). (c) 2006 Elsevier Ltd. All rights reserved.