Transcriptome Encyclopedia of Early Human Development.

Transcriptome Encyclopedia of Early Human Development.
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DOI:
10.1016/j.cell.2016.04.042
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发表时间:
2016-05-05
期刊:
影响因子:
64.5
通讯作者:
Plath K
Plath K
中科院分区:
生物学1区
文献类型:
--
作者:
Sahakyan A;Plath K

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我们对人类植入前发育的了解受到人类胚胎可获得性的限制,不能完全依赖于小鼠的研究。Petropoulos等人。现在提供了大量单细胞分辨率的人类植入前胚胎的广泛转录组分析,揭示了以前未被认识到的早期人类发育特有的特征。
Our understanding of human pre-implantation development is limited by the availability of human embryos and cannot completely rely on mouse studies. Petropoulos et al. now provide an extensive transcriptome analysis of a large number of human pre-implantation embryos at single-cell resolution, revealing previously unrecognized features unique to early human development.