ELECTRON-MICROSCOPIC AND RADIOISOTOPIC STUDIES ON CAP FORMATION IN TOXOPLASMA-GONDII
ELECTRON-MICROSCOPIC AND RADIOISOTOPIC STUDIES ON CAP FORMATION IN TOXOPLASMA-GONDII
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DOI：
10.1128/iai.14.5.1196-1201.1976
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发表时间：
1976-01-01
影响因子：
3.1
通讯作者：
PLONKA, WS
中科院分区：
文献类型：
--
作者：
DZBENSKI, TH;MICHALAK, T;PLONKA, WS
小鼠腹膜渗出的弓形虫滋养体能够脱落先前被包裹的[人类]抗体。抗体首先被移动到寄生虫的前极，在那里它们形成一个帽。它们以抗原-抗体复合物的形式从极点释放到环境中。积累材料的内化从未遇到过。可能观察到的现象反映了寄生虫逃避宿主免疫反应的机制。
Trophozoites of T. gondii from mouse peritoneal exudate are capable of shedding [human] antibodies with which they were previously coated. The antibodies are first moved towards the anterior pole of the parasite, where they form a cap. From the pole they are shed into the environment in the form of antigen-antibody complexes. An internalization of the accumulated material was never encountered. Probably the observed phenomenon reflects a mechanism by which the parasite evades the host''s immune response.