Incidence, clinical analysis, and management of ovarian fibromas and fibrothecomas
Incidence, clinical analysis, and management of ovarian fibromas and fibrothecomas
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DOI：
10.1016/j.ajog.2008.03.053
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发表时间：
2008-11-01
影响因子：
9.8
通讯作者：
Koubaa, Abdelhamid
中科院分区：
文献类型：
--
作者：
Chechia, Abdellatif;Attia, Leila;Koubaa, Abdelhamid
目的：本研究的目的是确定卵巢纤维瘤和纤维卵泡膜瘤的发病率，诊断，治疗和组织学的特殊性。研究设计：这是一项回顾性研究的24例谁接受手术治疗卵巢纤维瘤和纤维卵泡膜瘤1994年1月至2006年12月。分析临床、超声、肿瘤标志物、治疗和组织学资料。结果：患者平均年龄49岁。13例患者已绝经。超声表现为卵巢高回声肿瘤6例，低回声肿瘤12例，混合性肿瘤6例，无回声肿瘤1例。癌抗原-125测定21例，3例异常。21例患者接受了剖腹手术。3例患者行腹腔镜手术;然而，1例因疑似肿瘤转为剖腹手术。结论：卵巢纤维瘤和纤维卵泡膜瘤少见，占卵巢肿瘤的3.3%。这些病变常发生在围绝经期和绝经期患者。临床、超声和肿瘤标志物数据仍然是目前卵巢肿瘤最好的术前方法。然而，诊断仍然是组织学的。
OBJECTIVE: The objective of the study was to identify the incidence, diagnosis, and therapeutic and histological particularities of ovarian fibromas and fibrothecomas.STUDY DESIGN: This was a retrospective study of 24 patients who underwent surgical treatment for ovarian fibromas and fibrothecomas between January 1994 and December 2006. Clinical, ultasonographic, tumor marker, therapeutic, and histologic data were analyzed.RESULTS: The mean age of patients was 49 years. Thirteen patients were menopausal. Ultrasonographic findings were ovarian echogenic tumor in 6 cases, hypoechogenic tumor in 12 cases, mixed tumor in 6 cases, and anechogenic tumor in 1 case. Cancer antigen-125 level measured in 21 cases was abnormal in 3 cases. Twenty-one patients underwent laparotomy. Three patients underwent laparoscopy; however, 1 was converted to laparotomy because of a suspected tumor. Histological findings were 16 fibromas and 9 fibrothecomas.CONCLUSION: Ovarian fibromas and fibrothecomas are uncommon, accounting for 3.3% of ovarian tumors. These lesions often occur in perimenopausal and menopausal patients. Clinical, ultasonographic, and tumor marker data remain the best preoperative approach currently available for ovarian tumors. However, the diagnosis remains histological.