Rotational diffusion measurements using polarization-dependent fluorescence correlation spectroscopy based on superconducting nanowire single-photon detector
Rotational diffusion measurements using polarization-dependent fluorescence correlation spectroscopy based on superconducting nanowire single-photon detector
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DOI：
10.1364/oe.23.032633
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发表时间：
2015-12-14
期刊：
影响因子：
3.8
通讯作者：
Kinjo, Masataka
中科院分区：
文献类型：
--
作者：
Yamamoto, Johtaro;Oura, Makoto;Kinjo, Masataka
传统的偏振相关荧光相关光谱（pol-FCS）需要两组光子探测器来消除亚微秒范围内的脉冲后噪声（双通道pol-FCS；DC-pol-FCS）。在本研究中，我们使用可见波长超导纳米线单光子探测器（单通道pol-FCS；SC-pol-FCS）成功实现了pol-FCS。所使用的检测器没有脉冲后噪声，因此无需 pol-FCS 中的双通道。此外，SC-pol-FCS 系统中的光学器件比传统系统中的光学器件更容易调整。因此，与传统的 DC-pol-FCS 系统相比，我们获得了更高的信噪比。因此，SC-pol-FCS 是获得 pol-FCS 测量的潜在有用系统，并且可以促进改进的旋转扩散研究。 (C) 2015年美国光学学会
Conventional polarization-dependent fluorescence correlation spectroscopy (pol-FCS) requires two sets of photon detectors to eliminate after-pulse noises (dual-channel pol-FCS; DC-pol-FCS) in the sub-microsecond range. In this study, we successfully realized pol-FCS using a visible-wavelength superconductive nanowire single-photon detector (single-channel pol-FCS; SC-pol-FCS). The detector used is free of after-pulse noises and thus eliminates the need for dual channels in pol-FCS. Further, the optics in the SC-pol-FCS system are easier to adjust than those in the conventional system. Consequently, we obtained higher signal-to-noise ratios compared with conventional DC-pol-FCS systems. Thus, SC-pol-FCS is a potentially useful system for obtaining pol-FCS measurements, and can facilitate improved rotational diffusion studies. (C) 2015 Optical Society of America