Loneliness and vascular biomarkers: the Dublin Healthy Ageing Study
Loneliness and vascular biomarkers: the Dublin Healthy Ageing Study
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DOI：
10.1002/gps.2695
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发表时间：
2012-01-01
影响因子：
4
通讯作者：
Lawlor, B. A.
中科院分区：
文献类型：
--
作者：
O'Luanaigh, C.;O'Connell, H.;Lawlor, B. A.
孤独感与身体健康状况不佳有关，孤独感的存在、心血管健康和炎症标志物之间存在联系。目的：探讨社区非痴呆老年人群血管疾病生物标志物与孤独感的关系。设计：基于社区的横断面评估。参与者：466名受试者，平均年龄75.45岁（SD, 6.06）。男性208例（44.6%）。结果：较高的HbA1c水平与孤独独立相关，而其他血管生物标志物与孤独无关。结论：孤独感与社区老年人HbA1c水平升高有关。这种联系的机制尚未阐明，但可能反映了孤独者的异常压力反应。版权所有：John Wiley & Sons， Ltd。
Background Loneliness has been associated with poor physical health and a link has been suggested between the presence of loneliness, cardiovascular health and inflammatory markers.Objective: To investigate the association between vascular disease biomarkers and loneliness in a community-dwelling non-demented elderly population.Design: cross-sectional community based assessment.Participants: 466 subjects with mean age 75.45 (SD, 6.06) years. 208 (44.6%) were male.Results: Higher levels of HbA1c, but not other vascular biomarkers were independently associated with being lonely.Conclusion: Loneliness was associated with raised levels of HbA1c in a community dwelling elderly population. The mechanism for this association has yet to be elucidated but may reflect an abnormal stress response in people who are lonely. Copyright (C) 2011 John Wiley & Sons, Ltd.