III. Inulin renal clearance in dairy cattle.
III. Inulin renal clearance in dairy cattle.
复制标题
三．
DOI：
10.3168/jds.s0022-0302(60)90352-0
复制
发表时间：
1960
影响因子：
3.5
通讯作者：
J. P. Mixner
中科院分区：
文献类型：
--
作者：
R. R. Anderson;J. P. Mixner
总结一个实用的方法来确定菊糖肾清除率（肾小球滤过率的肾脏）和牛的细胞外液的体积进行了描述，基于菊粉的分布和处置的动力学测量静脉输注后。出于这些目的，以最多2小时的不同时间间隔测定菊粉的血液水平。输注后。菊粉在大约45分钟内与身体的细胞外液达到平衡。（半衰期约为6分钟）。菊粉的分布体积计算为29.3%和15.3%的体重，分别在小牛和母牛。小牛和母牛的菊糖清除率分别为0.0089和0.0168/min，而相应的菊糖体积清除率分别为2.61和2.57ml。每分钟每公斤体重。
Summary A practical method for determining inulin renal clearance (the glomerular filtration rate of the kidneys) and the volume of the extracellular fluids of cattle is described, based on the measurement of the kinetics of inulin distribution and disposal after intravenous infusion. For these purposes the blood level of inulin was determined at varying time intervals up to 2hr. after infusion. Inulin had reached equilibrium with the extracellular fluids of the body in approximately 45min. (half-time of about 6min.). The volume of the distribution of inulin was calculated to be 29.3 and 15.3% of body weight in a calf and cow, respectively. The inulin fractional clearance rate in a calf and cow were 0.0089 and 0.0168 per minute, while the corresponding inulin volume clearances were 2.61 and 2.57ml. per minute per kilogram of body weight, respectively.