Benign intracranial hypertension in childhood: A review of 23 patients
Benign intracranial hypertension in childhood: A review of 23 patients
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儿童期良性颅内高压：23 例患者的回顾
DOI：
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发表时间：
1991
影响因子：
1.7
通讯作者：
J. Antony
中科院分区：
文献类型：
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作者：
K. Dhiravibulya;R. Ouvrier;I. Johnston;P. Procopis;J. Antony
摘要23例良性颅内高压（BIH）患者在悉尼的皇家亚历山德拉儿童医院接受了18年的治疗，直至1988年。 就诊时年龄范围为6个月至13岁5个月。男女比例为2.3：1。病因（有时是多种）包括：慢性中耳感染，30%;硬脑膜窦血栓形成，22%;头部损伤，13%维生素A过量，4%;四环素暴露，4%;和没有明显的原因，43%。头痛是最常见的临床症状，91%的患者出现，其次是呕吐，65%，视力模糊或复视，57%。96%的患者出现视乳头水肿，48%的患者出现外展神经麻痹，45%的患者出现视力损害。所有患者治疗后临床症状均改善，1例仅行腰椎穿刺。在17名接受类固醇治疗的患者中，10名患者康复，7名患者继续腰大池腹腔分流术。两名患者通过类固醇和利尿剂治疗康复。在最初仅用利尿剂治疗的2例患者中，1例恢复，1例随后需要分流。只有1例患者最初接受了腰大池腹腔分流术治疗。其中三名分流患者出现分流阻滞，需要翻修。没有人有永久性视力丧失或其他严重后遗症。
Abstract Twenty‐three patients with benign intracranial hypertension (BIH) were seen at the Royal Alexandra Hospital for Children, Sydney over an 18 year period to 1988. Age at presentation ranged from 6 months to 13 years and 5 months. The female to male ratio was 2.3: 1. The aetiological factors (sometimes multiple) included: chronic middle ear infection, 30%; dural sinus thrombosis, 22%; head injury, 13% Vitamin A overdosage, 4%; tetracycline exposure, 4%; and no apparent cause, 43%. Headache was the most common presenting symptom occurring in 91% of patients, followed by vomiting in 65% and blurred or double vision in 57%. Papilloedema occurred in 96% of patients, abducens palsy was noted in 48% and visual impairment in 45%. All patients improved clinically after treatment, one with lumbar puncture only. Of 17 patients treated with steroids, 10 patients recovered and seven patients went on to lumboperitoneal shunt. Two patients recovered with steroid and diuretic treatment. Of two patients initially treated with diuretics only, one recovered and one subsequently required a shunt. Only one patient was initially treated with a lumboperitoneal shunt. Three of the shunted patients had shunt block requiring revision. None had permanent visual loss or other significant sequelae.