ASSESSING PERSONS WITH HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) INFECTION USING THE BECK DEPRESSION INVENTORY - DISEASE PROCESSES AND OTHER POTENTIAL CONFOUNDS
ASSESSING PERSONS WITH HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) INFECTION USING THE BECK DEPRESSION INVENTORY - DISEASE PROCESSES AND OTHER POTENTIAL CONFOUNDS
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DOI：
10.1207/s15327752jpa6401_5
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发表时间：
1995-02-01
影响因子：
3.4
通讯作者：
SOMLAI, A
中科院分区：
文献类型：
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作者：
KALICHMAN, SC;SIKKEMA, KJ;SOMLAI, A
人类免疫缺陷病毒（HIV）感染的症状和抑郁症的躯体症状重叠，混淆了HIV感染者的临床评估。这项研究考察了这种混淆的程度。在研究1中，71名HIV感染者在贝克抑郁量表（BDI）中表现出高抑郁率。然而，抑郁得分与艾滋病毒感染的症状相关。在研究2中，63名艾滋病毒感染者在BDI上也表现出高抑郁率，抑郁再次与艾滋病毒疾病的症状有关；具体来说，就是持续疲劳、腹泻、盗汗和肌肉疼痛。主成分因子分析表明，抑郁的躯体症状与获得性免疫缺陷综合征的诊断次数、hiv相关症状的数量密切相关，与t辅助细胞的数量呈负相关。相比之下，认知情感抑郁症与焦虑、疑病症和HIV检测呈阳性的月数密切相关。结果支持这样的结论，即抑郁评分需要在HIV疾病的不同阶段进行不同的解释，并且经历过HIV相关症状的人只能使用没有躯体症状的工具来评估抑郁。
Symptoms of Human Immunodeficiency Virus (HIV) infection and somatic symptoms of depression overlap, confounding clinical assessments of persons with HIV infection. This research examined the extent of this confounding. In Study 1, 71 persons with HIV infection demonstrated high rates of depression on the Beck Depression Inventory (BDI). However, depression scores correlated with symptoms of HIV infection. In Study 2, 63 persons with HIV infection also demonstrated high rates of depression on the BDI, and depression was again related to symptoms of HIV disease; specifically, persistent fatigue, diarrhea, night sweats, and muscle aches. Principal component factor analyses demonstrated that somatic symptoms of depression were closely associated with number of Acquired Immunodeficiency Syndrome diagnoses, number of HIV-related symptoms, and inversely related to number of T-helper cells. In contrast, cognitive-affective depression was most closely related to anxiety, hypochondriasis, and number of months since tested HIV positive. Results support the conclusion that depression scores require differential interpretations at different stages of HIV disease and that persons who have experienced HIV-related symptoms only be assessed for depression using instruments void of somatic symptoms.