Increasing incidence of candidemia:: Results from a 20-year nationwide study in Iceland
Increasing incidence of candidemia:: Results from a 20-year nationwide study in Iceland
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DOI：
10.1128/jcm.40.9.3489-3492.2002
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发表时间：
2002-09-01
影响因子：
9.4
通讯作者：
Gottfredsson, M
中科院分区：
文献类型：
--
作者：
Asmundsdóttir, LR;Erlendsdóttir, H;Gottfredsson, M
1980年至1999年在冰岛进行了一项关于念珠菌的全国性研究。年发病率从1980 ~ 1984年的1.4例/10万居民/年上升到1995 ~ 1999年的4.9例/10万居民/年（P < 0.0001）。大学医院念珠菌发生率从0.15/ 1000例增加到0.55/ 1000例（P < 0.0001）。白色念珠菌为优势菌种（64.4%）。在研究的后半段，氟康唑的国家进口量增加了大约四倍，但未观察到对该药物的耐药性增加。
A nationwide study on candidemia was conducted in Iceland from 1980 to 1999. The annual incidence increased from 1.4 cases/100,000 inhabitants/year between 1980 and 1984 to 4.9 cases/100,000 inhabitants/year between 1995 and 1999 (P < 0.0001). Candidemia episodes at university hospitals increased from 0.15/1,000 admissions to 0.55/1,000 admissions (P < 0.0001). Candida albicans was the predominant species responsible (64.4%). The national import of fluconazole increased approximately fourfold during the second half of the study, but increased resistance to this agent was not observed.