Estimation of pharyngeal residue after swallowing by retronasal aroma
Estimation of pharyngeal residue after swallowing by retronasal aroma
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DOI：
10.1111/joor.12974
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发表时间：
2020-04-24
影响因子：
2.9
通讯作者：
Ono, Takahiro
中科院分区：
文献类型：
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作者：
Okawa, Jumpei;Hori, Kazuhiro;Ono, Takahiro
背景咽部残留物可引发吞咽后误吸和窒息。已经进行了各种研究来评估咽部残留物的量;然而，尚未建立简单且定量的方法。咽部残留物释放的香气被认为是通过呼气经咽部（即鼻后通道）从咽部传递到鼻腔的目的本研究验证了咽部残留物的量可以通过香气强度来估计。在休息时或吞咽香精后，通过管将不同量的香精分配到咽部。通过将香精保留在咽部而不吞咽来模拟咽部残留物。气味传感器被放置在鼻孔中，保留的香精的香气强度随时间的推移measured over time.Results香气强度水平平坦后，一段时间已经过去了，和一个显着的相关性被发现之间分配的香精的量和平坦的香气强度，在休息和吞咽后。此外，为了在短时间内估计，通过拟合衰减曲线来估计香气强度随时间的变化。估计的强度收敛，计算从拟合曲线从80至120秒后吞咽，显着相关的测量intensity.Conclusion量咽残留物可以估计在很短的时间内通过测量的香气强度。
Background Pharyngeal residue can trigger aspiration and choking after swallowing. Various studies to assess the amount of pharyngeal residue have been conducted; however, an easy and quantitative method is yet to be established. The aroma released from the pharyngeal residue is thought to be delivered from the pharynx to the nasal cavity via velopharynx by expiration, that is, retronasal pathway.Objective This study verified that the amount of pharyngeal residue could be estimated by aroma intensity.Methods Ten healthy adult subjects had tubes in from the oral cavity to the pharynx. Varying amounts of essence were dispensed into the pharynx through the tube either at rest or after swallowing the essence. Pharyngeal residue was simulated by retention essence in the pharynx without swallowing. An odour sensor was placed in the nostril, and the aroma intensity of the retained essence was measured over time.Results The aroma intensity level flattened after a certain period of time had elapsed, and a significant correlation was found between the amount of essence dispensed and the flattened aroma intensity, both at rest and after swallowing. Furthermore, to estimate in a short period of time, changes in aroma intensity over time were estimated by fitting to a decay curve. The estimated intensity at convergence, calculated from the fitted curve from 80 to 120 seconds after swallowing, was significantly correlated to the measured intensity.Conclusion The amount of pharyngeal residue can be estimated in a short period of time by measuring the aroma intensity.