A retrospective study of human African Trypanosomiasis in three Malawian Districts.
A retrospective study of human African Trypanosomiasis in three Malawian Districts.
复制标题
马拉维三个地区人类非洲锥虫病的回顾性研究。
DOI：
10.4314/thrb.v13i1.61014
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发表时间：
2011
影响因子：
--
通讯作者：
Stone Kabuluzi
中科院分区：
文献类型：
--
作者：
J. Chisi;A. Muula;B. Ngwira;Stone Kabuluzi
人类非洲锥虫病（HAT）是一种被忽视的热带病（NTD）。许多流行地区的监测往往不够。在马拉维，艾滋病毒/艾滋病在某些地区流行，关于马拉维艾滋病毒/艾滋病情况的最新信息为提高对该疾病的认识和对预防和控制的兴趣提供了机会。在马拉维的三个地区：Nkotakota、Rumphi和Kasungu进行了一项回顾性研究，以描述HAT的流行情况。使用了2000年1月至2006年12月的医院实验室登记簿。经计算，地区锥虫病年度流行率从2000年的每100 000人0.29例到2003年的每100 000人0.58例不等。2002年，恩霍塔科塔区的锥虫病病例检出率最高，为每100 000人中16.56例，2004年的检出率最低，为每100 000人中5.23例。从2004年起，发现的病例有所下降。在伦披县，2003年发现的病例数最高（每100 000人中有17.67例），2001年的发病率最低，为每100 000人中有1.29例。2003年的发病率（每100 000人17.67例）比2002年（每100 000人3.02例）增加了5倍。在卡松古，2001、2003和2004年的发现率为每10万人0例，2005年为每10万人0.99例。该地区的病例数一直很低，包括2006年，当时的发现率为每10万人0.16例。HAT在马拉维的某些地区流行。有必要探讨主动疾病监测和建立永久性预防和控制措施的可行性。
Human African Trypanosomiasis (HAT) is a neglected tropical disease (NTD). Surveillance in many of the endemic areas is often inadequate. Up to date information on the HAT situation in Malawi, where the disease is endemic in some districts, provides opportunity to raise the profile of the disease and interest in prevention and control. A retrospective study was conducted in three Malawian districts: Nkhotakota, Rumphi and Kasungu to describe the prevalence of HAT. Hospital laboratory registers from January 2000 to December 2006 were used. The calculated annual district prevalence of Trypanosomiasis ranged from 0.29 cases per 100,000 population in 2000, to 0.58 cases per 100,000 population in 2003. Nkhotakota District had the highest case detection rate of trypanosomiasis of 16.56 cases per 100,000 in 2002 and the lowest rate in 2004 of 5.23 cases per 100,000. From 2004 onwards a decline in cases detected was observed. In Rumphi district the highest number of cases (17.67 cases per 100,000 population) was identified in 2003 and the lowest rate of 1.29 cases per 100,000 in 2001. The rate (17.67 cases per 100,000) found in 2003 represented a 5-fold increase of 2002 (3.02 cases per 100,000). In Kasungu the detection rate ranged from 0 per 100,000 in 2001, 2003 and 2004 to 0.99 cases per 100,000 in 2005. The number of cases in this district has remained low including in 2006, when a detection rate of 0.16 cases per 100,000 was observed. HAT is endemic in selected districts of Malawi. There is need to explore the feasibility of active disease surveillance and the establishment of permanent preventive and control measures.