Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines
Three-Component One-Pot Approach to Synthesize Benzopyrano[4,3-d]pyrimidines
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三组分一锅法合成苯并吡喃并[4,3-d]嘧啶
DOI:
10.1021/cc100173b
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发表时间:
2010-11-01
影响因子:
--
通讯作者:
Hu, Youhong
中科院分区:
文献类型:
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作者:
Li, Dewen;Duan, Shudong;Hu, Youhong
A novel benzopyrano[4,3-d]pyrimidine scaffold was generated via a three-component one-pot reaction from iodochromone, alkyne, and an amidine through a Sonogashira coupling, condensation, and cycloaddition. This combinatorial synthetic approach provides an efficient, easy construction of a diversified heterocyclic compounds library.