Effects of resistance training in healthy older people with sarcopenia: a systematic review and meta-analysis of randomized controlled trials.
Effects of resistance training in healthy older people with sarcopenia: a systematic review and meta-analysis of randomized controlled trials.
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DOI：
10.1186/s11556-021-00277-7
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发表时间：
2021-11-11
期刊：
影响因子：
--
通讯作者：
Liu Y
中科院分区：
文献类型：
--
作者：
Chen N;He X;Feng Y;Ainsworth BE;Liu Y
我们进行了一项荟萃分析，以分析阻力训练对老年肌肉减少症患者身体成分、肌肉力量和肌肉表现的影响。在Pubmed、Embase、科克伦图书馆、中国知网（CNKI）和万方数据库中检索所有关于阻力训练对老年肌肉减少症患者结局变量影响的随机对照试验。回顾了2010年1月至2020年10月的数据。两名研究人员独立提取数据并评估符合纳入标准的研究质量。前后变化的荟萃分析计算为标准化均值差（SMD）和95%置信区间（CI）。14项符合纳入标准的研究包括561名患有肌肉减少症的健康老年人（年龄65.8至82.8岁）。与对照组相比，抗阻训练对体脂量有积极影响（SMD =-0.53，95% CI − 0.81至− 0.25，p = 0.0002，I2 = 0%），握力（SMD = 0.81，95%CI 0.35 - 1.27，p = 0.0005，I2 = 81%），膝关节伸展强度（SMD = 1.26，95% CI 0.72至1.80，p < 0.0001，I2 = 67%），步态速度（SMD = 1.28，95%CI 0.36至2.19，p = 0.006，I2 = 89%），以及定时启动测试（SMD =-0.93，95%CI − 1.30至− 0.56，p < 0.0001，I2 = 23%）。抗阻训练对骨骼肌质量无明显影响（SMD = 0.25，95% CI − 0.27至0.78，p = 0.35，I2 = 68%），骨骼肌质量（SMD = 0.27，95% CI − 0.02至0.56，p = 0.07，I2 = 0%）和腿部瘦体重（SMD = 0.12，95% CI − 0.25至0.50，p = 0.52，I2 = 0%）。不同年龄、性别或诊断标准、体重的老年少肌症患者，经过不同干预时间、频率、方式和强度的抗阻训练后，其肌肉质量、握力、伸膝力量和肌肉性能的增益不同。阻力训练是一种有效的治疗方法，以改善身体脂肪量，肌肉力量和肌肉性能的健康老年人与肌肉减少症。在线版本包含补充材料，可通过10.1186/s11556-021-00277-7获得。
We conducted a meta-analysis to analyze the effects of resistance training on measures of body composition, muscle strength, and muscle performance in older people with sarcopenia. All randomized controlled trials on the effects of resistance training on outcome variables in older people with sarcopenia were searched on Pubmed, Embase, Cochrane Library, the China National Knowledge Infrastructure (CNKI), and Wanfang. Data from January 2010 to October 2020 were reviewed. Two researchers extracted data and evaluated the quality of the studies that met the inclusion criteria independently. Meta-analysis for pre-post changes were calculated as standardized mean difference (SMD) with 95% confidence intervals (CI). Fourteen studies meeting inclusion criteria included 561 healthy older adults (age 65.8 to 82.8) with sarcopenia. Compared with the control group, resistance training had positive effects on body fat mass (SMD = -0.53, 95% CI − 0.81 to − 0.25, p = 0.0002, I2 = 0%), handgrip strength (SMD = 0.81, 95%CI 0.35 to 1.27, p = 0.0005, I2 = 81%), knee extension strength (SMD = 1.26, 95% CI 0.72 to 1.80, p < 0.0001, I2 = 67%), gait speed (SMD = 1.28, 95%CI 0.36 to 2.19, p = 0.006, I2 = 89%), and the timed up and go test (SMD = -0.93, 95% CI − 1.30 to − 0.56, p < 0.0001, I2 = 23%). Resistance training had no effects on appendicular skeletal muscle mass (SMD = 0.25, 95% CI − 0.27 to 0.78, p = 0.35, I2 = 68%), skeletal muscle mass (SMD = 0.27, 95% CI − 0.02 to 0.56, p = 0.07, I2 = 0%) and leg lean mass (SMD = 0.12, 95% CI − 0.25 to 0.50, p = 0.52, I2 = 0%). Old people with sarcopenia of different ages, genders or diagnostic criteria and weights have different gains in muscle mass, handgrip strength, knee extension strength and muscle performance after different intervention duration, frequencies, mode and intensity resistance training. Resistance training is an effective treatment to improve body fat mass, muscle strength, and muscle performance in healthy older people with sarcopenia. The online version contains supplementary material available at 10.1186/s11556-021-00277-7.
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影响因子：
4.1
作者：
Chiu, Shu-Ching;Yang, Rong-Sen;Chang, Shu-Fang
通讯作者：
Chang, Shu-Fang
影响因子：
1.6
作者：
Hu, Xiaoyi;Jiang, Jiaojiao;Yang, Ming
通讯作者：
Yang, Ming
DOI：
10.23736/s1973-9087.17.04443-4
发表时间：
2017-08-01
影响因子：
4.5
作者：
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通讯作者：
Liou, Tsan-Hon
影响因子：
4.1
作者：
Hamaguchi K;Kurihara T;Fujimoto M;Iemitsu M;Sato K;Hamaoka T;Sanada K
通讯作者：
Sanada K
影响因子：
1.5
作者：
Cebria i Iranzo, Maria A.;Balasch-Bernat, Merce;Balasch-Parisi, Sebastia
通讯作者：
Balasch-Parisi, Sebastia