Attachment but not penetration of bovine herpesvirus 1 is necessary to induce apoptosis in target cells
Attachment but not penetration of bovine herpesvirus 1 is necessary to induce apoptosis in target cells
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DOI：
10.1128/jvi.72.9.7638-7641.1998
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发表时间：
1998-09-01
影响因子：
5.4
通讯作者：
Pastoret, PP
中科院分区：
文献类型：
--
作者：
Hanon, E;Meyer, G;Pastoret, PP
牛疱疹病毒1型（BHV-1）诱导牛外周血单个核细胞和B淋巴瘤细胞凋亡。使用BHV-1糖蛋白H无效突变体，我们已经证明，虽然BHV-1的渗透是不需要的，附着的BHV-1病毒颗粒是必不可少的诱导细胞凋亡。
Bovine herpesvirus 1 (BHV-1) induces apoptotic cell death in bovine peripheral blood mononuclear cells and B-lymphoma cells. Using a BHV-1 glycoprotein H null mutant, we have demonstrated that although penetration of BHV-1 is not required, attachment of BHV-1 viral particles is essential for the induction of apoptosis.