Four psychrotolerant species with high chemical diversity consistently producing cycloaspeptide A, Penicillium jamesonlandense sp nov., Penicillium ribium sp nov., Penicillium soppii and Penicillium lanosum
Four psychrotolerant species with high chemical diversity consistently producing cycloaspeptide A, Penicillium jamesonlandense sp nov., Penicillium ribium sp nov., Penicillium soppii and Penicillium lanosum
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DOI：
10.1099/ijs.0.64160-0
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发表时间：
2006-06-01
影响因子：
2.8
通讯作者：
Overy, David P.
中科院分区：
文献类型：
--
作者：
Frisvad, Jens C.;Larsen, Thomas O.;Overy, David P.
詹姆逊青霉是一种来自格陵兰岛的新物种，它在25摄氏度的温度下生长异常缓慢，最适生长温度为17-18摄氏度。该新物种比迄今描述的任何其他青霉物种都更耐冷。这一新物种的分离株产生一系列具有高度化学多样性的次生代谢物，以曲酸、青霉酸、灰黄霉素、伪黄素、金丝桃素、类胰蛋白酶和环肽为代表。里氏青霉是美国怀俄明州落基山脉的另一种新的耐冷菌，它能产生阿斯呋喃、曲酸和环肽。环肽A最初是从尼泊尔分离的一种未知曲霉中分离出来的，是从两个新的青霉种和两个已知的具有高度化学多样性的耐冷菌中首次报道的，它们是青霉和绵羊青霉。除金黄色葡萄球菌外，所有物种都能产生环肽和灰黄霉素的混合物。然而，核假单胞菌(3/5株)产生灰黄霉素的前体去甲己酮。詹姆斯兰青霉的模式菌株。11月为DACM 234087(T)(=IBT 21984(T)=IBT 24411(T)=CBS 102888(T))，为模式菌株。11月是234091(T)(=iBt 16537(T)=iBt 24431(T))。
Penicillium jamesonlandense is a novel species from Greenland that grows exceptionally slowly at 25 degrees C and has an optimum temperature for growth of 17-18 degrees C. The novel species is more psychrotolerant than any other Penicillium species described to date. Isolates of this novel species produce a range of secondary metabolites with a high chemical diversity, represented by kojic acid, penicillic acid, griseofulvin, pseurotin, chrysogine, tryptoquivalins and cycloaspeptide. Penicillium ribium, another novel psychrotolerant species from the Rocky Mountains, Wyoming, USA, produces asperfuran, kojic acid and cycloaspeptide. Originally reported from an unidentified Aspergillus species isolated from Nepal, cycloaspeptide A is reported here for the first time from the two novel Penicillium species and two known psychrotolerant species with high chemical diversity, Penicillium soppii and Penicillium lanosum. All species, except P. ribium, produce a combination of cycloaspeptide, and griseofulvin. However, P. ribium (3/5 strains) produced the precursor to griseofulvin, norlichexanthone. The type strain of Penicillium jamesonlandense sp. nov. is DACM 234087(T) (= IBT 21984(T)= IBT 24411(T) = CBS 102888(T)) and the type strain of Penicillium ribium sp. nov. is DAOM 234091(T) (= IBT 16537(T) = IBT 24431(T)).