The health risks of smoking. The Framingham Study: 34 years of follow-up.
The health risks of smoking. The Framingham Study: 34 years of follow-up.
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DOI：
10.1016/1047-2797(93)90070-k
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发表时间：
1993-07-01
影响因子：
5.6
通讯作者：
Kannel, W B
中科院分区：
文献类型：
--
作者：
Freund, K M;Belanger, A J;Kannel, W B
这项研究总结了吸烟率和累积剂量对弗雷明汉原始队列的健康的影响，5209人在进入时年龄在30至62岁之间。经过34年的随访，观察到吸烟是慢性咳嗽的主要决定因素，并降低了用力肺活量和1秒用力呼气量。研究发现，吸烟与肺癌、中风和短暂性脑缺血发作、间歇性跛行和心血管疾病的发病率，尤其是年平均死亡率之间存在显著关系。在45至64岁的男性中，吸烟与冠心病有显著关系，但与女性或老年男性无关。这些数据证实并扩大了吸烟对健康有害影响的证据。
This study summarizes the effects of both the rate and the cumulative dose of cigarette smoking on the health of the original Framingham cohort, 5209 individuals aged 30 to 62 years at entry. After 34 years of follow-up, it was observed that cigarette smoking was the prime determinant of chronic cough, and reduced both forced vital capacity and the 1-second forced expiratory volume. A significant relationship was observed between cigarette smoking and the incidence of cancer of the lung, stroke and transient ischemic attacks, intermittent claudication, and total cardiovascular disease, and most especially the average annual death rate. Cigarette smoking was significantly related to coronary heart disease in men 45 to 64 years old, although not related in women or older men. The data confirm and extend the evidence of the detrimental influence of cigarette smoking on health.