Racial/ethnic disparities in the use of nicotine replacement therapy and quit ratios in lifetime smokers ages 25 to 44 years

Racial/ethnic disparities in the use of nicotine replacement therapy and quit ratios in lifetime smokers ages 25 to 44 years
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DOI:
10.1158/1055-9965.epi-07-2726
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发表时间:
2008-07-01
影响因子:
3.8
通讯作者:
Bierut, Laura
Bierut, Laura
中科院分区:
医学3区
文献类型:
--
作者:
Fu, Steven S.;Kodl, Molly M.;Bierut, Laura

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我们研究了年龄在25至44岁之间的白人、非洲裔美国人、亚洲人和拉丁裔终身吸烟者使用尼古丁替代疗法(NRT)和戒烟率的种族/民族差异。我们使用尼古丁依赖遗传学协作研究中筛选入组的个体(n = 27,031)的数据进行了横断面分析。从2003年3月至2005年8月,使用密歇根州底特律市和明尼阿波利斯市的健康维护组织成员名单以及密苏里州圣路易斯市的驾驶执照登记处,从中西部三个大都市地区随机抽取参与者。电话调查收集了有关吸烟史、既往戒烟尝试和社会人口学特征的信息。在终生吸烟者(n = 9,216)中,单变量分析表明,非洲裔美国人(22%)和拉丁美洲人(22%)报告曾使用NRT戒烟的可能性显著低于白人(31%)。亚洲人(22%)报告的NRT使用率也低于高加索人,但该差异具有轻微显著性(P = 0.06)。在非裔美国人的多变量分析中,这些差异仍然存在[调整后的比值比(OR),0.76; 95%置信区间(95%CI),0.63-0.91; P < 0.01],但拉丁裔则不然(校正OR,0.76; 95% CI,0.54-1.06; P = 0.11)或亚洲人(校正OR,0.98; 95% CI,0.60-1.60; P = 0.95)。以戒烟率衡量,非裔美国人(35%)戒烟的可能性低于白人(52%)。这种差异在多变量logistic回归中持续存在(校正OR,0.66; 95%CI,0.56-0.78; P < 0.001)。亚裔和拉丁裔吸烟者报告戒烟的可能性与高加索人一样。未来的前瞻性研究需要评估是否较低的戒烟治疗,如NRT的使用有助于观察到的差异,戒烟率为非洲裔美国人。
We examined racial/ethnic variations in the use of nicotine replacement therapy (NRT) and quit ratios among Caucasian, African American, Asian, and Latino lifetime smokers ages 25 to 44 years. We conducted cross-sectional analyses using data from individuals (n = 27,031) screened for enrollment in the Collaborative Study of the Genetics of Nicotine Dependence. Participants were randomly sampled from three Midwestern metropolitan areas using Health Maintenance Organization membership lists in Detroit, MI and Minneapolis, MN and a driver's license registry in St. Louis, MO from March 2003 to August 2005. A telephone survey collected information on smoking history, previous quit attempts, and sociodemographic characteristics. Among lifetime smokers (n = 9,216), univariate analysis indicated that African Americans (22%) and Latinos (22%) were significantly less likely to report having ever used NRT for smoking cessation than Caucasians (31%). Asians (22%) also reported lower rates of using NRT than Caucasians, but this difference was marginally significant (P = 0.06). These disparities persisted in multivariate analysis for African Americans [adjusted odds ratio (OR), 0.76; 95% confidence interval (95% Cl), 0.63-0.91; P < 0.01] but not for Latinos (adjusted OR, 0.76; 95% Cl, 0.54-1.06; P = 0.11) or Asians (adjusted OR, 0.98; 95% CI, 0.60-1.60; P = 0.95). As measured by the quit ratio, African Americans (35%) were less likely to have quit smoking than Caucasians (52%). This disparity persisted in multivariate logistic regression (adjusted OR, 0.66; 95% Cl, 0.56-0.78; P < 0.001). Asian and Latino smokers were as likely as Caucasians to report smoking cessation. Future prospective studies are needed to assess whether lower utilization of cessation treatments such as NRT contribute to the observed disparity in quit ratios for African Americans.