DIFFERENTIATION OF THE SEXUALLY DIMORPHIC NUCLEUS IN THE PREOPTIC AREA OF THE RAT-BRAIN IS DETERMINED BY THE PERINATAL HORMONE ENVIRONMENT
DIFFERENTIATION OF THE SEXUALLY DIMORPHIC NUCLEUS IN THE PREOPTIC AREA OF THE RAT-BRAIN IS DETERMINED BY THE PERINATAL HORMONE ENVIRONMENT
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DOI：
10.1016/0304-3940(82)90388-3
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
GORSKI, RA
中科院分区：
文献类型：
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作者：
DOHLER, KD;COQUELIN, A;GORSKI, RA
雄性大鼠脑视前区（SDN-POA）两性二态核的体积比雌性大几倍。当雌性大鼠在出生前和出生后接受丙酸睾酮（TP）治疗时，它们的SDN-POA的大小与正常雄性相当。结果表明，在性别脑分化的关键时期，SDN-POA体积的总体形态性别差异完全受激素环境的控制。
The volume of a sexually dimorphic nucleus in the preoptic area (SDN-POA) of the rat brain is several fold larger in males than in females. When female rats were treated pre- and postnatally with testosterone propionate (TP) their SDN-POA developed equivalent in size to that of normal males. The results indicate that the gross morphological sex difference in SDN-POA volume is exclusively controlled by the hormonal environment during the critical period of sexual brain differentiation.