Regulatory T cells and inflammatory bowel disease
Regulatory T cells and inflammatory bowel disease
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DOI：
10.1016/s0167-5699(99)01510-8
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发表时间：
1999-10-01
期刊：
影响因子：
--
通讯作者：
Powrie, F
中科院分区：
文献类型：
--
作者：
Groux, H;Powrie, F
最近的研究发现，白介素10是一种新的免疫抑制调节性T细胞亚群的分化因子。在这里，Herve Groux和Fiona Powrie讨论了这些细胞在调节对肠道抗原的免疫反应中所起的作用，并提出这些细胞的缺陷可能参与了炎症性肠病的发病机制。
Recent studies have identified interleukin 10 as a differentiation factor for a novel subset of immune suppressive regulatory T cells. Here, Herve Groux and Fiona Powrie discuss the role that these cells play in the regulation of immune responses to enteric antigens and suggest that a deficiency in these cells might be involved in the pathogenesis of inflammatory bowel disease.