Upper and lower gastrointestinal endoscopical investigation in elderly patients with iron deficiency anaemia.
Upper and lower gastrointestinal endoscopical investigation in elderly patients with iron deficiency anaemia.
复制标题
老年缺铁性贫血患者的上、下消化道内镜检查。
DOI：
10.1163/15685590160141350
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
M. Karıncaoğlu
中科院分区：
文献类型：
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作者：
R. Sari;İ. Aydoğdu;A. Sevinç;M. Karıncaoğlu
缺铁性贫血常见于成年男性和绝经后女性，原因是慢性隐匿性出血，通常来自胃肠道。实际上，由于胃肠道系统的内镜检查是一种侵入性手术，即使在一线卫生机构，铁替代治疗通常也是在未调查潜在病因的情况下开始的。本研究评价了95例年龄为64.9 ± 12.5岁（范围50-90岁）的患者（51例男性，44例女性）的内镜检查在贫血病因学研究中的作用。所有缺铁性贫血患者均行上消化道内镜和结肠镜检查。分别在10例（10.6%）和55例（57.8%）患者中观察到上消化道和下消化道病变。缺铁性贫血30例（31.6%）无胃肠道病变。糜烂性胃炎16例（16.9%），十二指肠溃疡15例（15.8%），胃溃疡8例（8.4%），胃肿瘤7例（7.3%），食管炎7例（7.3%）。5例（5.4%）结肠肿瘤、3例（3.2%）痔疮、2例（2.1%）非热带口炎性腹泻、1例（1%）结肠息肉和1例（1%）结肠炎。老年缺铁性贫血患者以上消化道疾病为主，研究组12例（12.7%）合并恶性肿瘤。老年缺铁性贫血患者在补铁前应明确病因。
Iron deficiency anaemia is frequently observed in male adults and postmenopausal women due to chronic occult bleeding, usually from the gastrointestinal tract. Practically, as endoscopical investigation of the gastrointestinal system is an invasive procedure, iron replacement treatment was generally started without investigation of the underlying aetiology even in first-line health institutions. This study evaluates the role of endoscopy in the investigation of the aetiology of anaemia in 95 patients (51 males, 44 females), aged 64.9+/-12.5 years (range 50-90 years). All patients having iron deficiency anaemia were investigated by upper gastrointestinal endoscopy and colonoscopy. Upper and lower gastrointestinal pathologies were seen in 10 (10.6%) and 55 (57.8%) patients, respectively. However, no gastrointestinal lesion was found in 30 (31.6%) patients with iron deficiency anaemia. Out of the 95 patients, 16 (16.9%) had erosive gastritis, 15 (15.8%) duodenal ulcer, 8 (8.4%) gastric ulcer, 7 (7.3%) gastric tumours, 7 (7.3%) oesophagitis. 5 (5.4%) colon tumours, 3 (3.2%) haemorrhoids, 2 (2.1%) non-tropical sprue, 1 (1%) colonic polyp, and 1 (1%) colitis. In the majority of elderly patients with iron deficiency anaemia, upper gastrointestinal system disease was found. In 12 (12.7%) patients in the study group, malignancies were detected. In elderly patients with iron deficiency anaemia, the aetiology should be highlighted before giving iron supplementation.