A copper- and amine-free Sonogashira-type coupling procedure catalyzed by oxime palladacycles
A copper- and amine-free Sonogashira-type coupling procedure catalyzed by oxime palladacycles
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DOI：
10.1016/s0040-4039(02)02335-3
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发表时间：
2002-12-16
影响因子：
1.8
通讯作者：
Pacheco, MC
中科院分区：
文献类型：
--
作者：
Alonso, DA;Nájera, C;Pacheco, MC
在有机溶剂中，在110 ℃和高TON（高达72000）条件下，用1当量的四丁基乙酸铵，由4，4 '-二氯二苯甲酮衍生的肟钯化合物可促进芳基碘和芳基溴与末端乙炔的Sonogashira反应，反应时间一般为1 h。(C)2002爱思唯尔科技有限公司版权所有。
Oxime palladacycle derived from 4,4'-dichlorobenzophenone was found to promote the Sonogashira reaction of aryl iodides and aryl bromides with terminal acetylenes using I equivalent of tetrabutylammonium acetate in organic solvents generally in 1 h at 110degreesC and in high TONs (up to 72000). (C) 2002 Elsevier Science Ltd. All rights reserved.