Cost Savings of Mother's Own Milk for Very Low Birth Weight Infants in the Neonatal Intensive Care Unit.
Cost Savings of Mother's Own Milk for Very Low Birth Weight Infants in the Neonatal Intensive Care Unit.
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在新生儿重症监护病房中，母亲自身的牛奶为非常低的出生体重婴儿节省了成本。
DOI：
10.1007/s41669-022-00324-8
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发表时间：
2022-05
期刊：
影响因子：
--
通讯作者：
Meier PP
中科院分区：
文献类型：
--
作者：
Johnson TJ;Patel AL;Schoeny ME;Meier PP
这项研究的目的是确定极低出生体重(VLBW；<；)婴儿在最初的新生儿重症监护病房(NICU)住院期间的住院费用与母亲自己母乳剂量(MoM)的关系。此外，由于在NICU住院期间摄入MOM与晚发性败血症、坏死性小肠结肠炎(NEC)和支气管肺发育不良(BPD)的风险降低有关，我们旨在量化这些潜在的早产并发症的增量成本。这项研究包括430名极低出生体重儿，他们参加了2008至2012年间在美国伊利诺伊州芝加哥拉什大学医学中心进行的母亲自产奶前瞻性队列研究中极低出生体重儿的纵向结局。NICU的住院费用包括住院费用、喂养费用和医生费用。通过广义线性回归估计MOM剂量和已知通过MOM摄入减少的早产相关并发症对NICU住院费用的平均边际影响。NICU平均住院费用为190,586美元(标准差为119,235美元)。脓毒症的边际成本为27,890美元(95%可信区间为2934-52,646美元)，NEC为46,103美元(95%可信区间为16,829-75,377美元)，BPD为41,976美元(95%可信区间为24,660-59,292美元)。在NICU住院期间，MOM的累积比例与费用没有显著相关性。减少母亲摄入可能可以预防的并发症的发生率具有显著的成本影响。医院应该优先投资于支持NICU母亲喂养的倡议。网上版载有补充材料，可在10.1007/s41669.022-00324-8查阅。
The study aim was to determine the relationship between hospitalization costs and mother’s own milk (MOM) dose for very low birth weight (VLBW; < 1500 g) infants during the initial neonatal intensive care unit (NICU) stay. Additionally, because MOM intake during the NICU hospitalization is associated with a reduction in the risk of late-onset sepsis, necrotizing enterocolitis (NEC), and bronchopulmonary dysplasia (BPD), we aimed to quantify the incremental cost of these potentially preventable complications of prematurity. The study included 430 VLBW infants enrolled in the Longitudinal Outcomes of Very Low Birthweight Infants Exposed to Mothers' Own Milk prospective cohort study between 2008 and 2012 at Rush University Medical Center in Chicago, IL, USA. NICU hospitalization costs included hospital, feeding, and physician costs. The average marginal effect of MOM dose and prematurity-related complications known to be reduced by MOM intake on NICU hospitalization costs were estimated using generalized linear regression. The mean NICU hospitalization cost was $190,586 (standard deviation $119,235). The marginal cost of sepsis was $27,890 (95% confidence interval [CI] $2934–$52,646), of NEC was $46,103 (95% CI $16,829–$75,377), and of BPD was $41,976 (95% CI $24,660–59,292). The cumulative proportion of MOM during the NICU hospitalization was not significantly associated with cost. A reduction in the incidence of complications that are potentially preventable with MOM intake has significant cost implications. Hospitals should prioritize investments in initiatives to support MOM feedings in the NICU. The online version contains supplementary material available at 10.1007/s41669-022-00324-8.
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影响因子：
2.9
作者：
Beam, Andrew L.;Fried, Inbar;Armstrong, Joanne
通讯作者：
Armstrong, Joanne
影响因子：
2
作者：
Austin, Peter C.
通讯作者：
Austin, Peter C.
影响因子：
5.1
作者：
Johnson, Tricia J.;Patel, Aloka L.;Jegier, Briana J.;Engstrom, Janet L.;Meier, Paula P.
通讯作者：
Meier, Paula P.
影响因子：
3.5
作者：
Manning, WG;Mullahy, J
通讯作者：
Mullahy, J
影响因子：
26.1
作者：
Lapcharoensap, Wannasiri;Gage, Susan C.;Lee, Henry C.
通讯作者：
Lee, Henry C.