Further Studies on the Developmental Change in Myotrophic Activity of Chicken Serum: Relation between Activity and Transferrin
Further Studies on the Developmental Change in Myotrophic Activity of Chicken Serum: Relation between Activity and Transferrin
复制标题
鸡血清肌营养活性发育变化的进一步研究：活性与转铁蛋白的关系
DOI：
10.1111/j.1440-169x.1983.00523.x
复制
发表时间：
1983
期刊：
影响因子：
4.6
通讯作者：
E. Ozawa
中科院分区：
文献类型：
--
作者：
I. Kimura;E. Ozawa
作为先前研究的延伸，我们重新检查了鸡血清对体外鸡肌原性细胞的营养活性的发育变化，并试图根据血清转铁蛋白（Tf）的可能变化来阐明它，其肌营养活性取决于其浓度和铁饱和度水平。肌营养活性在卵内第2周之前较低，然后在孵化时突然增加到一个平台，然后下降到成虫水平。血清Tf的浓度和铁饱和度水平的测定表明，肌营养活性的变化主要由这两个参数引起，但也可能涉及其他因素。
As an extension of previous studies, we reexamined the developmental change in trophic activity of chicken serum on chicken myogenic cells in vitro and attempted to elucidate it on the basis of possible changes in serum transferrin (Tf), the myotrophic activity of which depends both on its concentration and on the level of its iron‐saturation. The myotrophic activity was found to be low until the second week in ovo, then to increase rather abruptly to a plateau at about the time of hatching, and then to decrease to the adult level. Determination of the concentration and level of iron‐saturation of serum Tf suggested that the change in myotrophic activity was mainly caused by these two parameters, though another factor(s) may also be involved.