Use of color kinesis for evaluation of left ventricular filling in patients with dilated cardiomyopathy and mitral regurgitation.
Use of color kinesis for evaluation of left ventricular filling in patients with dilated cardiomyopathy and mitral regurgitation.
复制标题
使用颜色运动评估扩张型心肌病和二尖瓣关闭不全患者的左心室充盈。
DOI：
10.1016/s0735-1097(98)00144-2
复制
发表时间：
1998
影响因子：
24
通讯作者：
R. Lang
中科院分区：
文献类型：
--
作者：
I. Godoy;V. Mor;L. Weinert;P. Vignon;C. Korcarz;K. Spencer;R. Lang
Objectives. We tested the feasibility of using analysis of color kinesis images to objectively assess global and regional left ventricular (LV) diastolic function in patients with dilated cardiomyopathy (DCM). In addition, the ability of this technique to track drug-induced changes on LV diastolic properties was studied.Background. Diastolic dysfunction contributes to symptomatology in patients with DCM. The assessment of LV diastolic function using conventional Doppler echocardiography is indirect and is confounded by multiple variables. Moreover, the noninvasive evaluation of regional diastolic properties is difficult. In contrast, color kinesis directly tracks and color-encodes regional diastolic endocardial motion.Methods. We studied 24 patients with DCM and mitral regurgitation (MR) and 24 age-matched normal subjects. Transmitral and pulmonary vein flow velocities were measured using pulsed Doppler echocardiography. Diastolic color kinesis images were used to calculate indexes of magnitude and timing of global and regional diastolic function. Diastolic asynchrony was evaluated in different subgroups of patients with DCM. The effects of drug infusions (nitroprusside and dobutamine) were also studied.Results. Color kinesis indexes of global diastolic function showed significant differences between patients with DCM and normal subjects. Compared with Doppler indexes, color kinesis was less confounded by MR and was capable of differentiating between drug-induced lusitropic and vasodilator effects. Diastolic asynchrony was increased in patients with DCM and severe MR.Conclusions. Quantitative analysis of global and regional LV diastolic function in patients with DCM using color kinesis is feasible.
影响因子：
37.8
作者：
MASSIE, B;CONWAY, M;RAJAGOPALAN, B
通讯作者：
RAJAGOPALAN, B
正性肌力药物和血管扩张剂治疗对充血性心肌病患者舒张特性的不同影响。
影响因子：
37.8
作者：
Carroll,JD;Lang,RM;Neumann,AL;Borow,KM;Rajfer,SI
通讯作者：
Rajfer,SI