A prospective randomized multicenter clinical evaluation of an anterior cervical fusion cage
A prospective randomized multicenter clinical evaluation of an anterior cervical fusion cage
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DOI：
10.1097/00007632-200010150-00017
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发表时间：
2000-10-15
期刊：
影响因子：
3
通讯作者：
Griffith, SL
中科院分区：
文献类型：
--
作者：
Hacker, RJ;Cauthen, JC;Griffith, SL
研究设计.一项关于前路Bagby和Kuslich颈椎融合器（巴克/C; Sulzer Spine-Tech，Minneapolis，MN）治疗颈椎退行性椎间盘疾病的前瞻性、同期对照、随机、多中心试验。报告使用巴克/C融合器进行融合的最长24个月随访的临床结果。背景数据总结。在过去的十年中，螺纹腰椎融合器已被用作慢性致残性腰痛的安全有效的手术解决方案。现已开发出用于颈前路椎间融合的螺纹融合器，以避免：需要进行同种异体移植或自体骨移植手术，同时在融合过程中提供初始稳定性。白色。方法。有症状的颈椎椎间盘源性神经根病患者接受颈椎前路椎间盘切除术联合非内固定骨融合（ACDF）或巴克/C融合器治疗。对融合进行独立的影像学评估，并通过视觉模拟疼痛量表和简明健康状况量表（SF）-36评估基于患者的结局。数据分析包括1年时的344例患者和2年时的180例患者。当两个笼子组（羟基磷灰石、涂层或非涂层）与ACDF组相比，在手术持续时间、住院时间、患肢颈部疼痛和神经根疼痛改善、SF-86身体分量表和精神分量表改善以及患者对总体手术结局的感知方面观察到相似的结局：2年时症状改善得以维持。ACDF患者需要髂嵴取骨的比例高于巴克/C患者（67% vs. 3%）。12个月时，巴克/C组单节段手术的融合成功率为97.9%，ACDF组为89.7%（P
Study Design. A prospective, concurrently controlled randomized, multicenter trial of an anterior Bagby and Kuslich cervical fusion cage (BAK/C; Sulzer Spine-Tech, Minneapolis, MN) for treatment of degenerative disc disease of the cervical spine.Objectives. To report clinical results with maximum 24-month follow-up of fusions performed with the BAK/C fusion cage.Summary of Background Data. Threaded lumbar cages have been used during the past decade as a safe and effective surgical solution for chronic disabling low back pain. Threaded cages have now been developed for use in anterior cervical interbody fusions to obviate:the need for allografts or autogenous bone grafting procedures white providing initial stability during the fusion process.Methods. Patients with symptomatic cervical discogenic radiculopathy were treated with either anterior cervical discectomy with uninstrumented bone-only fusion (ACDF) or BAK/C fusion cage(s). Independent radiographic assessment of fusion was made and: patient-based outcome was assessed by visual analog pain scale and a Short Form (SF)-36 Health Status Questionnaire.Results. Data analysis included 344 patients at 1 year and 180 at 2 years. When the two cage groups (hydroxya, patite-coated or noncoated) were compared with the ACDF group, similar outcomes were noted for duration of surgery, hospital stay, improvements in neck pain and radicular pain in the affected limb, improvements:in the SF-86 Physical Component subscale and Mental Component subscale, and the patients' perception of overall surgical outcome: Symptom improvements were maintained at 2 years A greater percentage of patients with ACDF needed an iliac crest bone harvest than did BAK/C patients (67% vs. 3%). Successful fusion for one-level procedures at 12 months was 97.9% for the BAK/C groups and 89.7% Cor the ACDF group (P