Vulvar basal cell carcinoma: retrospective study and review of literature
Vulvar basal cell carcinoma: retrospective study and review of literature
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DOI：
10.1016/j.ygyno.2004.12.008
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发表时间：
2005-04-01
影响因子：
4.7
通讯作者：
Carli, P
中科院分区：
文献类型：
--
作者：
de Giorgi, V;Salvini, C;Carli, P
目标。基底细胞癌（BCC）是最常见的人类恶性肿瘤。它不仅发生在经常暴露在阳光下的解剖区域，而且还发生在相对受保护的身体部位，如腋窝、腹股沟和臀部，以及完全不受阳光照射的区域，如外阴。本研究的目的是评估外阴基底细胞癌相对于其他解剖部位的影响和临床特征。方法。为此，我们回顾性回顾了1995年至2003年意大利佛罗伦萨大学人类病理学和肿瘤学系对BCC的所有组织学诊断结果。在 3604 例 BCC 病例中，63 例发生在外阴。后者患者的平均年龄为70.35岁。外阴 BCC 的平均大小为 2.1 cm，18 个 (28%) 就诊时已溃烂。结论。我们的研究表明，外阴基底细胞癌并不是一种特别罕见的疾病。事实上，只要我们认为炎症性病变对常规治疗没有反应，就应该怀疑它。根据我们的经验，特别是对于有皮肤癌病史的患者，应该对该解剖区域进行皮肤粘膜检查。如有怀疑，建议进行活检以获得术前确诊。 (c) 2004 Elsevier Inc. 保留所有权利。
Objectives. Basal Cell Carcinoma (BCC) is the most common human malignant neoplasm. It does not occur only in anatomical areas commonly exposed to sunlight, but also in relatively protected body sites such as the axillae, the groin and buttocks, and in regions which are entirely protected from the sun, like the vulva. The aim of this study is to assess the impact and clinical features of BCCs in the vulva versus other anatomical sites.Methods. For this purpose, we retrospectively reviewed all the histological diagnoses of BCCs made between 1995 and 2003 in the Department of Human Pathology and Oncology of the University of Florence, Italy.Results. Out of 3604 cases of BCC, 63 were in the vulva. The average age of patients suffering from the latter was 70.35 years. The average size of the vulvar BCCs was 2.1 cm and 18 (28%) were ulcerated at presentation.Conclusions. Our study shows that vulvar BCC is not a particularly rare occurrence; in fact it Should be Suspected whenever lesions that we believe to be inflammatory do not respond to usual treatment. In our experience, mucocutaneous examination of this anatomical area should be performed especially in patients with a history of skin cancer. In case of suspicion, a biopsy is recommended to obtain a preoperative confirmatory diagnosis. (c) 2004 Elsevier Inc. All rights reserved.