Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing
Responsive and reactive terbium complexes with an azaxanthone sensitiser and one naphthyl group: applications in ratiometric oxygen sensing in vitro and in regioselective cell killing
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DOI：
10.1039/b920222f
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发表时间：
2009-01-01
影响因子：
4.9
通讯作者：
Wong, Ka-Leung
中科院分区：
文献类型：
--
作者：
Law, Ga-Lai;Pal, Robert;Wong, Ka-Leung
设计了一种铽配合物，可用于敏感单线态氧（phi(em) 12%）的形成，允许创建pO(2)的比例感应系统（相对于不敏感的Eu类似物），并定义了一种反应性探针，可用于对负载该配合物并暴露于激光激发下的细胞造成局部损伤。
A terbium complex has been designed that may be used to sensitise formation of singlet oxygen (phi(em) 12%), allowing the creation of a ratiometric sensory system for pO(2) ( versus the insensitive Eu analogue) and the definition of a reactive probe that can be used to cause local damage to cells loaded with the complex and exposed to laser excitation.