Comorbidity in the prediction of Cognitive Processing Therapy treatment outcomes for combat-related posttraumatic stress disorder

Comorbidity in the prediction of Cognitive Processing Therapy treatment outcomes for combat-related posttraumatic stress disorder
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DOI:
10.1016/j.janxdis.2013.12.002
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发表时间:
2014-03-01
影响因子:
10.3
通讯作者:
Forbes, D.
Forbes, D.
中科院分区:
医学2区
文献类型:
--
作者:
Lloyd, D.;Nixon, R. D. V.;Forbes, D.

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本文探讨了澳大利亚退伍军人认知加工治疗(CPT)后创伤后应激障碍(PTSD)治疗结果的临床预测因素。59名寻求治疗的退伍军人参加了一项随机对照试验,比较了三个社区退伍军人咨询中心的12次CPT(n =30)与常规治疗(n = 29)。测量了PTSD和主要共病(抑郁、焦虑、愤怒和饮酒)。生长曲线模型被用来检查影响治疗后PTSD严重程度的因素。对于CPT条件,基线愤怒是PTSD严重程度随时间变化的唯一共病预测。随着时间的推移,愤怒分数较高的参与者的PTSD严重程度下降较少。参与者的焦虑程度越高,治疗效果越好。这项研究表明,经历高水平愤怒的退伍军人可能会受益于有针对性的愤怒减少策略,以提高CPT治疗PTSD的有效性。皇冠版权所有(C)2014由爱思唯尔有限公司出版。保留所有权利。
This paper examines clinical predictors of posttraumatic stress disorder (PTSD) treatment outcomes following Cognitive Processing Therapy (CPT) in Australian military veterans. Fifty nine treatment seeking veterans were enrolled in a randomized controlled trial comparing 12 sessions of CPT (n =30) with usual treatment (n = 29) at three community-based veterans counseling centers. PTSD and key co-morbidities (depression, anxiety, anger and alcohol use) were measured. Growth curve modeling was used to examine factors which influenced PTSD severity post-treatment. For the CPT condition, baseline anger was the only co-morbidity predictive of change in PTSD severity over time. Participants with higher anger scores showed less of a decrease in PTSD severity over time. Higher anxiety in participants in treatment as usual was significantly associated with better treatment gains. This research suggests that veterans experiencing high levels of anger might benefit from targeted anger reduction strategies to increase the effectiveness of CPT treatment for PTSD. Crown Copyright (C) 2014 Published by Elsevier Ltd. All rights reserved.