Do fast foods cause asthma, rhinoconjunctivitis and eczema? Global findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three
Do fast foods cause asthma, rhinoconjunctivitis and eczema? Global findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three
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DOI：
10.1136/thoraxjnl-2012-202285
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发表时间：
2013-04-01
期刊：
影响因子：
10
通讯作者：
Nagel, Gabriele
中科院分区：
文献类型：
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作者：
Ellwood, Philippa;Asher, M. Innes;Nagel, Gabriele
背景某些食物可能会增加或降低患哮喘、鼻结膜炎和湿疹的风险。方法对13~14岁青少年和6~7岁儿童的父母/监护人进行问卷调查，了解12个月来儿童哮喘、鼻结膜炎和湿疹的症状患病率以及食物摄入的种类和频率。结果对于青少年和儿童，每周食用3次水果对重度哮喘有潜在的保护作用(OR=0.89，95%CI为0.82~0.97；OR 0.86，95%CI为0.76~0.97)。青少年和儿童患严重哮喘的风险增加与每周食用3次快餐有关(OR1.39，95%CI 1.30至1.49；OR 1.27，95%CI 1.13至1.42)，以及严重鼻结膜炎和严重湿疹的风险增加。在区域分析中观察到两个年龄段的相似模式，并与性别和富裕类别以及所有三种疾病的当前症状一致。结论如果快餐与哮喘、鼻结膜炎和湿疹的症状患病率之间存在因果关系，那么由于全球快餐消费的增加，这一发现具有重大的公共卫生意义。
Background Certain foods may increase or decrease the risk of developing asthma, rhinoconjunctivitis and eczema. We explored the impact of the intake of types of food on these diseases in Phase Three of the International Study of Asthma and Allergies in Childhood.Methods Written questionnaires on the symptom prevalence of asthma, rhinoconjunctivitis and eczema and types and frequency of food intake over the past 12 months were completed by 13-14-year-old adolescents and by the parents/guardians of 6-7-year-old children. Prevalence ORs were estimated using logistic regression, adjusting for confounders, and using a random (mixed) effects model.Results For adolescents and children, a potential protective effect on severe asthma was associated with consumption of fruit >= 3 times per week (OR 0.89, 95% CI 0.82 to 0.97; OR 0.86, 95% CI 0.76 to 0.97, respectively). An increased risk of severe asthma in adolescents and children was associated with the consumption of fast food >= 3 times per week (OR 1.39, 95% CI 1.30 to 1.49; OR 1.27, 95% CI 1.13 to 1.42, respectively), as well as an increased risk of severe rhinoconjunctivitis and severe eczema. Similar patterns for both ages were observed for regional analyses, and were consistent with gender and affluence categories and with current symptoms of all three conditions.Conclusions If the association between fast foods and the symptom prevalence of asthma, rhinoconjunctivitis and eczema is causal, then the findings have major public health significance owing to the rising consumption of fast foods globally.