MYCOBACTERIUM-KANSASII INFECTIONS IN WESTERN-AUSTRALIA (1962-1987)

MYCOBACTERIUM-KANSASII INFECTIONS IN WESTERN-AUSTRALIA (1962-1987)
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DOI:
10.1016/s0954-6111(06)80082-x
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发表时间:
1991-05-01
影响因子:
4.3
通讯作者:
PANG, SC
PANG, SC
中科院分区:
医学3区
文献类型:
--
作者:
PANG, SC

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本文回顾了西澳大利亚州26年来分离出的81例堪萨斯分枝杆菌患者的记录。39例40次感染被认为是由toM引起的疾病。堪萨斯州:肺部36例(90%),关节2例(5%),皮肤(2.5%)和淋巴结各1例(2.5%)。平均发病率为每10万人每年0.14,最高的是杰拉尔顿中西部地区(0.57)。男女比例为4:1,平均年龄50岁(sd14.5)。肺部疾病的男女比例为3.1:1,平均年龄53岁(sd11), 42%是矿工或前矿工,91%是吸烟者或前吸烟者。几乎97%的感染者是白种人,没有土著居民。药物治疗非常成功,特别是利福平/乙胺丁醇联合治疗,12个月似乎足够。与42例隔离不显著的患者相比,肺部疾病患者的人口统计学存在差异。
The records of 81 patients with isolations ofMycobacterium kansasiiin Western Australia over 26 years have been reviewed. Thirty-nine individuals with 40 episodes of infection were considered to have disease due toM. kansasii: 36 in the lungs (90%), two in the joints (5%), and one each in the skin (2·5%) and the lymph nodes (2·5%). The average incidence rate per 100 000 per year was 0·14 for the state with the highest in the Geraldton Mid-west region (0·57). The male:female ratio was 4:1 and the mean age 50 years (sd14·5). For pulmonary disease the male:female ratio was 3·5:1, the mean age 53 years (sd11), 42% being miners or ex-miners and 91% smokers or ex-smokers. Almost 97% of those infected were Caucasian and none were Aboriginal. Drug treatment was highly successful, particularly with the rifampicin/ethambutol combination, where 12 months appeared to be adequate. There are differences in the demography of the patients having pulmonary disease compared to the 42 with insignificant isolations.