Solid-Phase Microextraction: A Complementary In Vivo Sampling Method to Microdialysis
Solid-Phase Microextraction: A Complementary In Vivo Sampling Method to Microdialysis
复制标题
DOI：
10.1002/anie.201304538
复制
发表时间：
2013-11-11
影响因子：
16.6
通讯作者：
Pawliszyn, Janusz
中科院分区：
文献类型：
--
作者：
Cudjoe, Erasmus;Bojko, Barbara;Pawliszyn, Janusz
两个人的赞美：固相微萃取（SPME）在脑组织中选定神经递质的同时靶向分析中相对于微透析（MD）进行了验证。互补的数据，从全球的大脑分析与这两种方法。MD主要提取极性物质，SPME检测半疏水和疏水化合物，包括与神经退行性疾病相关的脂质。RT=保留时间。
Two's compliment: Solid‐phase microextraction (SPME) was validated against microdialysis (MD) in simultaneous targeted analysis of selected neurotransmitters in brain tissue. Complementary data was obtained from global brain profiling with both methods. MD extracts primarily polar species, and SPME detects semi hydrophobic and hydrophobic compounds, including lipids related to neurodegenerative diseases. RT= retention time.