Functional constipation in infants: a follow-up study.
Functional constipation in infants: a follow-up study.
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婴儿功能性便秘：一项后续研究。
DOI：
10.1016/j.jpeds.2005.05.032
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
M. Benninga
中科院分区：
文献类型：
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作者：
M. M. Berg;C. V. Rossum;F. Lorijn;J. Reitsma;C. Lorenzo;M. Benninga
本研究的目的是描述儿童早期严重功能性便秘的临床过程。符合条件的患者为47名儿童（60%为男孩;中位年龄为3.5个月），他们在出生后的第一年内患有便秘。通过标准化问卷调查获得随访数据。成功定义为至少持续4周，每周无痛排便≥3次。初步评估后6个月，69%的儿童康复。初步成功后，15%的儿童在3年内复发。转诊前症状持续时间<3个月与较好的结局显著相关。我们的结论是，大多数严重便秘的婴儿在三级中心评估6个月后恢复。早期治疗干预可能有助于便秘的解决。
Our objective of this study was to describe the clinical course of severe functional constipation in early childhood. Eligible patients were 47 children (60% boys; median age, 3.5 months) who had constipation in their first year of life. Follow-up data were obtained through a standardized questionnaire. Success was defined as a period of at least 4 weeks with ≥3 painless bowel movements per week. Six months after initial evaluation, 69% of the children were recovered. After initial success, a relapse occurred in 15% of the children within 3 years. A duration of symptoms <3 months before referral correlated significantly with better outcome. We conclude that most infants with severe constipation evaluated at a tertiary center are recovered after 6 months. Early therapeutic intervention may beneficially contribute to the resolution of constipation.