Mappings between a macroscopic neural-mass model and a reduced conductance-based model.

Mappings between a macroscopic neural-mass model and a reduced conductance-based model.
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宏观神经质量模型和基于简化电导的模型之间的映射。

DOI:
10.1007/s00422-010-0372-z
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发表时间:
2010
影响因子:
1.9
通讯作者:
Rodrigues S
Rodrigues S
中科院分区:
工程技术3区
文献类型:
--
作者:
Rodrigues S

文献摘要

相似文献

我们提出了宏观神经元模型和基于电导模型的简化之间的两种替代映射。这为这两种不同的神经元活动建模方法的参数之间的关系提供了可能的解释。获得神经团块模型的物理解释是至关重要的,因为它们可以为诊断神经系统疾病提供直接和可访问的工具。详细考虑每个映射的有效性所需的假设,阐明了每个宏观模型的优点和缺点,并为未来的发展提出了改进建议。
We present two alternative mappings between macroscopic neuronal models and a reduction of a conductance-based model. These provide possible explanations of the relationship between parameters of these two different approaches to modelling neuronal activity. Obtaining a physical interpretation of neural-mass models is of fundamental importance as they could provide direct and accessible tools for use in diagnosing neurological conditions. Detailed consideration of the assumptions required for the validity of each mapping elucidates strengths and weaknesses of each macroscopic model and suggests improvements for future development.