An ultra-sensitive and ratiometric fluorescent probe based on the DTBET process for Hg2+ detection and imaging applications
An ultra-sensitive and ratiometric fluorescent probe based on the DTBET process for Hg2+ detection and imaging applications
复制标题
基于 DTBET 工艺的超灵敏比例荧光探针，适用于 Hg2 检测和成像应用
DOI：
10.1039/c8an02126k
复制
发表时间：
2019-02-21
期刊：
影响因子：
4.2
通讯作者：
Ho, Derek
中科院分区：
文献类型：
--
作者：
Jiang, Yin;Duan, Qinya;Ho, Derek
在本文中，我们提出了一种基于聚集诱导发射（AIE）和暗键通能转移（DTBET）机制的用于Hg2+检测的超灵敏比率荧光探针（TR-Hg）。使用四苯乙烯作为暗供体和罗丹明 B 硫代内酯作为受体构建探针。利用DTBET消除暗供体发射泄漏并提供近100%能量转移效率的优势，TR-Hg在与Hg2+反应后表现出超过30000倍的荧光比增强。 TR-Hg 展示了 (i) 43 pM 的检测限，这是已报道的比例 Hg2+ 探针中最低的，(ii) 出色的选择性、快速的响应时间（
In this article, we present an ultra-sensitive and ratiometric fluorescent probe (TR-Hg) for Hg2+ detection based on the mechanism of aggregation induced emission (AIE) and dark through-bond energy transfer (DTBET). The probe was constructed using tetraphenylethene as the dark donor and rhodamine B thiolactone as the acceptor. By exploiting the advantages of DTBET, which eliminates emission leakage from dark donors and provides nearly 100% energy transfer efficiency, TR-Hg exhibits more than a 30000-fold fluorescence ratio enhancement after reacting with Hg2+. TR-Hg demostrates (i) a detection limit of 43 pM, which is the lowest among the reported ratiometric Hg2+ probes, (ii) excellent selectivity, fast response-time (