What about the "self" is processed in the posterior cingulate cortex?
What about the "self" is processed in the posterior cingulate cortex?
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DOI：
10.3389/fnhum.2013.00647
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发表时间：
2013-10-02
影响因子：
2.9
通讯作者：
Whitfield-Gabrieli, Susan
中科院分区：
文献类型：
--
作者：
Brewer, Judson A.;Garrison, Kathleen A.;Whitfield-Gabrieli, Susan
在过去的十年中，神经影像学研究已经开始确定参与自我参照处理的关键大脑区域，最一致的中线结构，如后扣带皮层（PCC）。大多数研究都采用了认知任务，如对特质形容词或走神的判断，这与PCC活动的增加有关。相反，共享以当前为中心的注意力元素（“任务”）的任务，从工作记忆到冥想，都与PCC活动减少有关。考虑到可能有助于这些任务的认知过程的复杂性，PCC对自我相关过程的具体贡献仍然未知。在此之前的文献的基础上，最近的研究采用了更精确地将主观体验与大脑活动联系起来的采样方法，例如实时fMRI神经反馈。最近的研究表明，PCC活动可能代表了自我参照的认知过程的一个子成分-“陷入”一个人的经验。例如，陷入对药物的渴望或特定的观点。在本文中，我们将审查证据在一些不同领域的认知神经科学，收敛在激活和失活的PCC，包括最近的神经现象学研究的PCC活动，使用实时功能磁共振成像神经反馈。
In the past decade, neuroimaging research has begun to identify key brain regions involved in self-referential processing, most consistently midline structures such as the posterior cingulate cortex (PCC). The majority of studies have employed cognitive tasks such as judgment about trait adjectives or mind wandering, that have been associated with increased PCC activity. Conversely, tasks that share an element of present-centered attention (being "on task"), ranging from working memory to meditation, have been associated with decreased PCC activity. Given the complexity of cognitive processes that likely contribute to these tasks, the specific contribution of the PCC to self-related processes still remains unknown. Building on this prior literature, recent studies have employed sampling methods that more precisely link subjective experience to brain activity, such as real-time fMRI neurofeedback. This recent work suggests that PCC activity may represent a sub-component cognitive process of self-reference - "getting caught up in" one's experience. For example, getting caught up in a drug craving or a particular viewpoint. In this paper, we will review evidence across a number of different domains of cognitive neuroscience that converges in activation and deactivation of the PCC including recent neurophenomenological studies of PCC activity using real-time fMRI neurofeedback.