Age-stratified sex differences in polysomnographic findings and pharyngeal morphology among children with obstructive sleep apnea
Age-stratified sex differences in polysomnographic findings and pharyngeal morphology among children with obstructive sleep apnea
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DOI：
10.21037/jtd.2018.11.09
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发表时间：
2018-12-01
影响因子：
2.5
通讯作者：
Ikeda, Katsuhisa
中科院分区：
文献类型：
--
作者：
Inoshita, Ayako;Kasai, Takatoshi;Ikeda, Katsuhisa
背景资料：儿童阻塞性睡眠呼吸暂停（OSA）对生长，学习，行为，认知和心血管健康以及成年后的打鼾和OSA具有重要意义。在这项研究中，我们阐明了儿童OSA patients.Methods的多导睡眠图（PSG）的结果和咽部X线片数据的性别差异：63名儿童（年龄在3至15岁之间）OSA [定义为呼吸暂停低通气指数（AHI）>= 1/h的多导睡眠图]。从患者中获得侧颈X线片。结果：共入组青春期前组45例（男33例，女12例），青春期组18例（男10例，女8例），比较各组性别差异。我们发现，在青少年组的颅面特征和严重程度的OSA的性别差异，其中OSA的女孩有更多的上气道空间，除了较低的AHI，较低的3%氧去饱和指数（ODI），较高的最低SO2和更好的睡眠效率比boy.Conclusions：本研究发现揭示了青少年组儿童OSA患者的性别差异。青春期组女生的上呼吸道空间大，AHI低，ODI低，最低SO2高，睡眠效率好。
Background: Childhood obstructive sleep apnea (OSA) has important implications for growth, learning, behavior, cognition and cardiovascular health as well as snoring and OSA in adulthood. In this study, we elucidated the sex differences in polysomnographic (PSG) findings and pharyngeal radiographic data in pediatric OSA patients.Methods: Sixty three children (age between 3 and 15 years old) with OSA [defined as apnea-hypopnea index (AHI) >= 1/h by polysomnography] were enrolled. Lateral neck radiographs were obtained from the patients. All subjects were separated by age: pre-adolescent group (3-8 years old) and adolescent group (9-15 years old).Results: Overall, 45 patients in the pre-adolescent group (33 boys and 12 girls) and 18 patients in the adolescent group (10 boys and 8 girls) were enrolled, and sex differences were compared in each group. We found sex differences in craniofacial features and severity of OSA in the adolescent group, in which girls with OSA had more upper airway space, in addition to lower AHI, lower 3% oxygen desaturation index (ODI), higher minimum SO2 and better sleep efficiency than the boys.Conclusions: The present study found revealed sex differences in pediatric OSA patients in the adolescent group. Girls in the adolescent group had more upper airway space in addition to lower AHI, lower 3% ODI, higher minimum SO2 and better sleep efficiency than boys.