Somatic symptoms for predicting depression: One-year follow-up study in annual health examinations
Somatic symptoms for predicting depression: One-year follow-up study in annual health examinations
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DOI：
10.1111/j.1440-1819.2006.01489.x
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发表时间：
2006-04-01
影响因子：
11.9
通讯作者：
Yano, E
中科院分区：
文献类型：
--
作者：
Nakao, M;Yano, E
最近有人指出，筛查抑郁症可以改善临床结果。本研究的目的是检查是否在健康检查报告的躯体症状预测抑郁症在接下来的一年。受试者为连续两年在某研究所参加年度健康检查的1066名日本工人（732名男性，平均年龄35岁）。采用自填式问卷调查法，对12项主要躯体症状进行调查。然后用DSM-IV的临床访谈来诊断这两年的重性抑郁和轻性抑郁。此外，17项汉密尔顿抑郁量表（HDS-17）被测量为第二年抑郁的结局之一。重度（轻度）抑郁症的患病率在基线时为3.7（7.8）%，次年为3.4（5.9）%。第二年的HDS-17评分，在基线时抱怨每种躯体症状的患者高于没有抱怨的患者（P < 0.05）。基线时的三种躯体症状（腰痛、头晕和腹痛）是次年重度抑郁症的重要危险因素。基线时的头晕也能显著预测下一年的重度和轻度抑郁。躯体症状可能是健康体检中筛查抑郁症的良好预测指标。
It has recently been noted that screening for depression can improve clinical outcomes. The purpose of the present study was to examine whether somatic symptoms reported at health examinations predicted depression in the following year. Subjects were 1066 Japanese workers (732 men, mean age 35 years) attending annual health examinations at an institute in two successive years. A self-administered questionnaire including items of 12 major somatic symptoms was given to all the subjects. Then clinical interviews of the DSM-IV were used to diagnose major depression and minor depression in both years. In addition, the 17-item Hamilton Depression Scale (HDS-17) was measured as one of the outcomes of depression in the following year. The prevalence of major (minor) depression was 3.7 (7.8)% at baseline and 3.4 (5.9)% for the following year, respectively. The following year's HDS-17 scores were higher (all P < 0.05) in those who had complained of each somatic symptom at baseline than in those who had not. Three somatic symptoms (low back pain, dizziness, and abdominal pain) at baseline were significant risk factors of major depression for the following year. Dizziness at baseline significantly predicted major and minor depression for the following year as well. Somatic symptoms may be good predictors to screen for depression at health examination.