Structure, gene order, and nucleotide composition of mitochondrial genomes in parasitic lice from Amblycera
Structure, gene order, and nucleotide composition of mitochondrial genomes in parasitic lice from Amblycera
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DOI：
10.1016/j.gene.2020.145312
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发表时间：
2021-01-05
期刊：
影响因子：
3.5
通讯作者：
Cameron, Stephen L.
中科院分区：
文献类型：
--
作者：
Sweet, Andrew D.;Johnson, Kevin P.;Cameron, Stephen L.
寄生虱具有独特的线粒体（mt）基因组，其特征在于重排的基因顺序，可变的基因组结构，和大多数其他昆虫相比AT含量较少。然而，对Amblycera的mt基因组知之甚少，Amblycera是所有其他寄生虱的姊妹亚目。通过对9个不同属（包括所有7个科的代表）的比较，我们发现Amblycera具有变异的和高度重排的mt基因组。有些属的基因组片段长度差异很大，而另一些属只有一条mt染色体。值得注意的是，这些基因组比大多数其他虱子更倾向于AT。我们还恢复了Amblycera之间属水平的系统发育关系，这些关系与大型核数据集报道的关系一致，表明MT序列对于重建Amblycera的进化关系是可靠的。然而，基因顺序数据不能可靠地恢复这些相同的关系。总的来说，我们的研究结果表明，虱子的mt基因组，已经知道是独特的，甚至比以前认为的更可变。
Parasitic lice have unique mitochondrial (mt) genomes characterized by rearranged gene orders, variable genome structures, and less AT content compared to most other insects. However, relatively little is known about the mt genomes of Amblycera, the suborder sister to all other parasitic lice. Comparing among nine different genera (including representative of all seven families), we show that Amblycera have variable and highly rearranged mt genomes. Some genera have fragmented genomes that vary considerably in length, whereas others have a single mt chromosome. Notably, these genomes are more AT-biased than most other lice. We also recover genus-level phylogenetic relationships among Amblycera that are consistent with those reported from large nuclear datasets, indicating that mt sequences are reliable for reconstructing evolutionary relationships in Amblycera. However, gene order data cannot reliably recover these same relationships. Overall, our results suggest that the mt genomes of lice, already know to be distinctive, are even more variable than previously thought.