Epidemiology of acute renal failure in ICUs: a multi-center prospective study.
Epidemiology of acute renal failure in ICUs: a multi-center prospective study.
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DOI：
10.1159/000231986
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发表时间：
2009-01-01
影响因子：
3
通讯作者：
Ronco, Claudio
中科院分区：
文献类型：
--
作者：
Andrikos, Emilios;Tseke, Paraskevi;Ronco, Claudio
背景与目的：急性肾损伤（阿基）是重症监护病房（ICU）常见的并发症。然而，其发病率和结果在几项研究中有所不同，这取决于所使用的定义甚至研究的地理来源。我们的目的是评估阿基在ICU在Greece.METHOD的流行病学：前瞻性多中心研究的ICU患者与阿基在3个月period.RESULTS：170例阿基（16%的总入院23 ICU）。阿基最常见的促成因素是脓毒症（45%）。一半的患者需要肾脏替代治疗，主要由ICU临床医生管理。近65%的阿基患者死亡，而15%的患者因肾损害而出院。年龄（RR 1.01，p = 0.046），脓毒症（RR 1.62，p = 0.015）和尿量（RR 0.99，p = 0.009）与预后独立相关。结论：阿基涉及希腊ICU的大量患者，并与不良结局相关。
BACKGROUND AND AIM: Acute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece.METHOD: Prospective multicenter study of ICU patients presented with AKI during a 3-month period.RESULTS: One-hundred and seventy patients presented with AKI (16% of total admissions in 23 ICUs). The most common contributing factor to AKI was sepsis (45%). Half of the patients required renal replacement therapy, which was mainly managed by ICU clinicians. Nearly 65% of the AKI patients died, whereas 15% were discharged with renal impairment. Age (RR 1.01, p = 0.046), sepsis (RR 1.62, p = 0.015) and urine output (RR 0.99, p = 0.009) were independently associated with outcome.CONCLUSION: AKI involves a large number of patients in Greek ICUs and is associated with adverse outcomes.