DIFFUSE AXONAL INJURY IN HEAD TRAUMA
DIFFUSE AXONAL INJURY IN HEAD TRAUMA
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DOI：
10.1136/jnnp.52.7.838
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发表时间：
1989-07-01
影响因子：
11
通讯作者：
NORTH, JB
中科院分区：
文献类型：
--
作者：
BLUMBERGS, PC;JONES, NR;NORTH, JB
弥漫性轴索损伤（DAI）是通过详细的显微镜检查定义的，在80例连续的头部创伤病例中，有34例存活了足够长的时间，由皇家阿德莱德医院神经外科部门进行临床评估。研究结果表明，有一系列的轴索损伤，三分之一的DAI病例恢复得足够好，从最初的头部损伤引起昏迷到随后的死亡。胼胝体和脑干背外侧象限的宏观“标记”病变仅出现在15/34的病例中，代表了DAI谱系中最严重的一端。
Diffuse axonal injury (DAI) as defined by detailed microscopic examination was found in 34 of 80 consecutive cases of head trauma surviving for a sufficient length of time to be clinically assessed by the Royal Adelaide Hospital Neurosurgery Unit. The findings indicate that there is a spectrum of axonal injury and that one third of the cases of DAI recovered sufficiently to talk between the initial head injury producing coma and subsequent death. The macroscopic "marker" lesions in the corpus callosum and dorsolateral quadrants of the brainstem were present in only 15/34 of the cases and represented the most severe end of the spectrum of DAI.