High-intensity resistance training improves glycemic control in older patients with type 2 diabetes
High-intensity resistance training improves glycemic control in older patients with type 2 diabetes
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DOI：
10.2337/diacare.25.10.1729
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发表时间：
2002-10-01
期刊：
影响因子：
16.2
通讯作者：
Zimmet, P
中科院分区：
文献类型：
--
作者：
Dunstan, DW;Daly, RM;Zimmet, P
研究设计和方法-久坐、超重的2型糖尿病男性和女性，年龄60-80岁（n = 36），随机分为高强度渐进式阻力训练加中度减肥组（RT & WL组）和中度减肥加对照组（WL组）。结果：RT & WL组HbA（1c）在3个月（0.6 +/- 0.7 vs. 0.07 +/-0.8%，P < 0.05）和6个月（1.2 +/- 1.0 vs. 0.4 +/-0.8%，P < 0.05）时比WL组下降更明显。6个月后观察到体重（RT WL 2.5 +/- 2.9 vs WL 3.1 +/- 2.1 kg）和脂肪量（RT WL 2.4 +/- 2.7 vs WL 2.7 2.5 kg）的相似降低。相比之下，6个月后，RT & WL组的瘦体重（LBM）增加（0.5 +/- 1.1 kg），WL组减少（0.4 +/- 1.0）（P < 0.05）。空腹血糖，胰岛素，血脂和脂蛋白，或静息血压没有组间差异。结论-高强度渐进阻力训练，结合适度减肥，是有效的改善血糖控制老年2型糖尿病患者。提高肌肉力量和LBM的其他好处确定高强度阻力训练是老年2型糖尿病患者管理计划中可行和有效的组成部分。
OBJECTIVE - To examine the effect of high-intensity progressive resistance training combined with moderate weight loss on glycemic control and body composition in older patients with type 2 diabetes.RESEARCH DESIGN AND METHODS- Sedentary, overweight men and women with type 2 diabetes, aged 60-80 years (n = 36), were randomized to high-intensity progressive resistance training plus moderate weight loss (RT & WL group) or moderate weight loss plus a control program (WL group). Clinical and laboratory measurements were assessed at 0, 3, and 6 months.RESULTS- HbA(1c) fell significantly more in RT & WL than WL at 3 months (0.6 +/- 0.7 vs. 0.07 +/- 0.8%, P < 0.05) and 6 months (1.2 +/- 1.0 vs. 0.4 +/- 0.8%, P < 0.05). Similar reductions in body weight (RT WL 2.5 +/- 2.9 vs. WL 3.1 +/- 2.1 kg) and fat mass (RT WL 2.4 +/- 2.7 vs. WL 2.7 2.5 kg) were observed after 6 months. In contrast, lean body mass (LBM) increased in the RT & WL group (0.5 +/- 1.1 kg) and decreased in the WL group (0.4 +/- 1.0) after 6 months (P < 0.05). There were no between-group differences for fasting glucose, insulin, serum lipids and lipoproteins, or resting blood pressure.CONCLUSIONS- High-intensity progressive resistance training, in combination with moderate weight loss, was effective in improving glycemic control in older patients with type 2 diabetes. Additional benefits of improved muscular strength and LBM identify high-intensity resistance training as a feasible and effective component in the management program for older patients with type 2 diabetes.