Eosinophilic Granulomatosis with Polyangiitis Initially Diagnosed as Eosinophilic Gastroenteritis
Eosinophilic Granulomatosis with Polyangiitis Initially Diagnosed as Eosinophilic Gastroenteritis
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DOI：
10.2169/internalmedicine.3391-19
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发表时间：
2020-01-01
影响因子：
1.2
通讯作者：
Kinoshita, Yoshikazu
中科院分区：
文献类型：
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作者：
Itawaki, Ayako;Okada, Mayumi;Kinoshita, Yoshikazu
我们在此报告两例嗜酸性肉芽肿合并多血管炎(EGPA)，最初仅根据内窥镜活检结果诊断为嗜酸性胃肠炎(EGE)。在EGE诊断一年后，一名患者出现多发性紫癜，皮肤活检结果导致诊断改为EGPA。另1例在诊断为EGE后8年出现多发性皮肤和结肠溃疡，此时内窥镜活检标本组织学检查发现血管炎，诊断改为EGPA。内科医生应该意识到在诊断为EGE的病例中可能存在EGPA。
We herein report two cases of eosinophilic granulomatosis with polyangiitis (EGPA) initially diagnosed as eosinophilic gastroenteritis (EGE) based solely on endoscopic biopsy results. One year after the EGE diagnosis, one patient presented with multiple purpura, and skin biopsy fmdings resulted in a change of the diagnosis to EGPA. In another patient, multiple skin and colonic ulcerations emerged eight years after the diagnosis of EGE, at which time histological examinations of endoscopic biopsy specimens revealed vasculitis, and the diagnosis was changed to EGPA. Physicians should be aware of the possible existence of EGPA in cases diagnosed as EGE.