Sex-determined variation in serum insulin and growth hormone response to amino acid stimulation.
Sex-determined variation in serum insulin and growth hormone response to amino acid stimulation.
复制标题
血清胰岛素和生长激素对氨基酸刺激的反应由性别决定。
DOI：
10.1210/jcem-26-7-791
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发表时间：
1966
期刊：
影响因子：
--
通讯作者：
D. Rabinowitz
中科院分区：
文献类型：
--
作者：
T. Merimee;J. A. Bergess;D. Rabinowitz
几个实验室报告了氨基酸给药后胰岛素和人生长激素（HGH）的血浆浓度升高（1-3）。在经验的过程中，与受试者谁给予精氨酸输注，我们观察到，女性受试者显示出更大的上升，血清胰岛素和血清生长激素比男性的年龄相当。氨基酸输注后男性和女性受试者之间的这些差异，以及己烯雌酚预处理（如己烯雌酚）增加HGH而不是胰岛素的能力，形成了本报告的基础。
Several laboratories have reported a rise in plasma concentrations of insulin and human growth hormone (HGH) following the administration of amino acids (1–3). During the course of experience with subjects who were given infusions of arginine, we observed that female subjects showed a greater rise in serum insulin and in serum HGH than did males of a comparable age. These differences between male and female subjects after amino acid infusion, and the ability of stilbestrol pretreatment (as diethylstilbestrol) to augment HGH, but not insulin, responsiveness in the male, form the basis of this report.