Disseminated cutaneous Mycobacterium chelonae infection in an immunocompetent host
Disseminated cutaneous Mycobacterium chelonae infection in an immunocompetent host
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DOI：
10.1111/j.1365-2230.2009.03416.x
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发表时间：
2010-04-01
影响因子：
4.1
通讯作者：
Tan, B. B.
中科院分区：
文献类型：
--
作者：
Halpern, J.;Biswas, A.;Tan, B. B.
龟分枝杆菌是一种罕见的、生长迅速的非典型抗酸杆菌。在免疫功能低下的患者中有播散性皮肤感染的报道。我们报告一位免疫功能正常的86岁白人妇女，她有8个月的广泛溃疡性脓肿样结节病史。分枝杆菌培养证实为龟分枝杆菌感染，患者给予克拉霉素和妥布霉素联合治疗。据我们所知，这是首次报道的自发性弥散性皮肤病发生在免疫功能正常的患者身上的病例。
P>Mycobacterium chelonae is a rare, rapidly growing, atypical acid-fast bacillus. Disseminated cutaneous infection has been reported in immunocompromised patients. We report an immunocompetent 86-year-old white woman, who presented with an 8-month history of extensive ulcerated abscess-like nodules. Mycobacterial culture confirmed M. chelonae infection and the patient was treated with a combination of clarithromycin and tobramycin. To our knowledge, this is the first reported case of spontaneous, disseminated cutaneous disease occurring in an immunocompetent patient.