A Strategy for Genomic Research on Common Cardiovascular Diseases Aiming at the Realization of Precision Medicine: Personal Insights and Perspectives.

A Strategy for Genomic Research on Common Cardiovascular Diseases Aiming at the Realization of Precision Medicine: Personal Insights and Perspectives.
复制标题

以实现精准医疗为目标的常见心血管疾病基因组研究策略:个人见解与展望。

DOI:
10.1161/circresaha.116.309802
复制
发表时间:
2016
影响因子:
20.1
通讯作者:
Komuro I.
Komuro I.
中科院分区:
医学1区
文献类型:
--
作者:
Morita H;Komuro I.

文献摘要

相似文献

Morita和Komuro关于常见心血管疾病的基因组研究901获得了最有用的发现,我们必须汇集下一代测序和多组学的精髓,从基因组,表观基因组,转录组,蛋白质组和代谢组到表型组。大量的基因组数据、临床数据及其相互作用的巨大复杂性应该得到有效的分析、整合并提交到公共数据库中。这应该是即将到来的基因组研究的支柱,以实现精准医学(图)。
Morita and Komuro Genomic Research on Common Cardiovascular Diseases 901 acquire the most useful findings, we have to bring together the essence of next-generation sequencing and multiomics from the genome, epigenome, transcriptome, proteome, and metabolome to the phenome. The huge volume of genomic data, clinical data, and the enormous complexity of their interplay should be effectively analyzed, integrated, and submitted into the public databases. This should be a mainstay for upcoming genomic research toward the realization of precision medicine (Figure).