Electrophysiology of vagal afferents: amino acid detection in the gut.
Electrophysiology of vagal afferents: amino acid detection in the gut.
复制标题
迷走神经传入的电生理学:肠道中的氨基酸检测。
DOI:
10.1111/j.1749-6632.2009.03907.x
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发表时间:
2009
影响因子:
5.2
通讯作者:
Horn,CharlesC
中科院分区:
文献类型:
--
作者:
Horn,CharlesC
The alimentary canal includes the mouth, stomach, and intestines, and is connected to the brain by thousands of chemosensory neurons. In contrast to the understanding of the lingual taste system, there is little insight into the chemosensory function of other regions of the alimentary canal. The presence of known taste receptors in the gastrointestinal tract suggests a similarity to taste mechanisms present in the oral cavity. Afferent fibers of the vagus play a prominent role in signaling the chemical contents of the gastrointestinal tract to the hindbrain and this information can be used to elicit defensive responses, such as vomiting or nutritional responses. A host of amino acids are likely detected by vagal afferent fibers, but the initial sensory transduction of these stimuli and functional significance remains a mystery. Several problems with recording the electrophysiological signals of vagal afferents are discussed, with particular reference to sampling the afferent signals from the duodenum and liver region.
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影响因子:
2.9
作者:
V. K. Chadha;B. Plapp
通讯作者:
B. Plapp
影响因子:
15
作者:
T. B. Johnson
通讯作者:
T. B. Johnson
影响因子:
4.1
作者:
S. Husain;G. Lowe
通讯作者:
G. Lowe
DOI:
--
发表时间:
1971
期刊:
Biochimica et Biophysica Acta
影响因子:
--
作者:
M. Steinberg;S. Cohen;W. Weber
通讯作者:
W. Weber
影响因子:
2.9
作者:
B. Fraij;F. C. Hartman
通讯作者:
F. C. Hartman