A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen
A simple method to estimate populational 24-h urinary sodium and potassium excretion using a casual urine specimen
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DOI：
10.1038/sj.jhh.1001307
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发表时间：
2002-02-01
影响因子：
2.7
通讯作者：
Hashimoto, T
中科院分区：
文献类型：
--
作者：
Tanaka, T;Okamura, T;Hashimoto, T
为了估计人群的盐和钾摄入量，并比较其年度趋势，我们开发了一种简单的方法来估计人口平均水平的24小时尿钠（24 HUNaV）和钾（24 HUKV）排泄从现场尿液标本收集在任何时间。使用来自INTERSALT研究的591个日本数据项作为金标准，我们开发了使用现场和24小时尿液采集样本估计24小时尿肌酐（24 HUCrV）、24 HUNaV和24 HUKV的公式。为了检验公式的准确性，我们将这些公式应用于513名外部体力劳动者。计算公式如下：（1）PRCr（mg/天）= -2.04 ×年龄+14.89 ×体重（kg）+16.14 ×身高（cm）-2244.45;（2）估算的24 HUNa V（mEq/天）= 21.98 × XNa 0.392;（3）估算的24 HUKV（mEq/天）= 7.59 × XK 0.431;其中PRCr = 24 HUCr的预测值，SUNa =点排尿中的Na浓度，SUK =点排尿中的K浓度，SUCr =点排尿中的肌酐浓度，XNa（或XK）= SUNa（或SUK）/SUCr × PRCr。在外部组中，钠（24.0 mmol/天）和钾（3.8 mmol/天）排泄的估计值和测量值之间存在显著但较小的差异。在每个五分位数除以估计的24 HUNaV或24 HUKV时，测量值与估计值平行。总之，虽然这种方法不适合估计个人钠和钾排泄，这些公式被认为是有用的估计人口平均水平的24小时钠和钾排泄，并可用于比较不同的人群，以及指示特定人群的年度趋势。
In order to estimate the salt and potassium intake in a population and to compare their annual trends, we developed a simple method to estimate population mean levels of 24-h urinary sodium (24HUNaV) and potassium (24HUKV) excretion from spot urine specimens collected at any time. Using 591 Japanese data items from the INTERSALT study as a gold standard, we developed formulas to estimate 24-h urinary creatinine (24HUCrV), 24HUNaV and 24HUKV using both spot and 24-h urine collection samples. To examine the accuracy of the formulas, we applied these equations to 513 external manual workers. The obtained formulas were as follows: (1) PRCr (mg/day) = -2.04 x age + 14.89 x weight (kg) + 16.14 x height (cm) - 2244.45; (2) estimated 24HUNaV (mEq/day) = 21.98 x XNa0.392; (3) estimated 24HUKV (mEq/day) = 7.59 x XK0.431; where PRCr = predicted value of 24HUCr, SUNa = Na concentration in the spot voiding urine, SUK = K concentration in the spot voiding urine, SUCr = creatinine concentration in the spot voiding urine, XNa (or XK) = SUNa (or SUK)/SUCr x PRCr. In the external group, there was a significant but small difference between the estimated and measured values in sodium (24.0 mmol/day) and potassium (3.8 mmol/day) excretion. In every quintile divided by the estimated 24HUNaV or 24HUKV, the measured values were parallel to the estimated values. In conclusion, although this method is not suitable for estimating individual Na and K excretion, these formulas are considered useful for estimating population mean levels of 24-h Na and K excretion, and are available for comparing different populations, as well as indicating annual trends of a particular population.