PATHFINDING BY PERIPHERAL PIONEER NEURONS IN GRASSHOPPERS
PATHFINDING BY PERIPHERAL PIONEER NEURONS IN GRASSHOPPERS
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DOI：
10.1126/science.218.4577.1082
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发表时间：
1982-01-01
期刊：
影响因子：
56.9
通讯作者：
KESHISHIAN, H
中科院分区：
文献类型：
--
作者：
BENTLEY, D;KESHISHIAN, H
蚱蜢神经元精确地在外周结构和中枢神经系统之间长距离投射轴突。在胚胎发生的早期，先锋神经元建立了由这些轴突跟随的神经干通路。来自第一批先行者的生长锥沿着细胞链导航到中枢神经系统。这些细胞的放置可能构成了长距离寻路的初始引导机制。
Grasshopper neurons accurately project axons across long distances between peripheral structures and the central nervous system. Nerve-trunk pathways followed by these axons are established early in embryogenesis by pioneer neurons. Growth cones from the first pioneers navigate along a chain of cells to the CNS. The placement of these cells may constitute the initial guidance mechanism underlying long-distance pathfinding.